评估肯尼亚缺氧儿童持续供氧储库储存系统的可行性研究。

A feasibility study evaluating a reservoir storage system for continuous oxygen delivery for children with hypoxemia in Kenya.

机构信息

Center for Public Health and Development, Nairobi, Kenya.

Intellectual Ventures Laboratory, Bellevue, WA, USA.

出版信息

BMC Pulm Med. 2021 Mar 5;21(1):78. doi: 10.1186/s12890-021-01433-6.

DOI:10.1186/s12890-021-01433-6

PMID:33663453

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7934496/

Abstract

BACKGROUND

Supplemental oxygen is an essential treatment for childhood pneumonia but is often unavailable in low-resource settings or unreliable due to frequent and long-lasting power outages. We present a novel medium pressure reservoir (MPR) which delivers continuous oxygen to pediatric patients through power outages.

METHODS

An observational case series pilot study assessing the capacity, efficacy and user appraisal of a novel MPR device for use in low-resource pediatric wards. We designed and tested a MPR in a controlled preclinical setting, established feasibility of the device in two rural Kenyan hospitals, and sought user feedback and satisfaction using a standardized questionnaire.

RESULTS

Preclinical data showed that the MPR was capable of bridging power outages and delivering a continuous flow of oxygen to a simulated patient. The MPR was then deployed for clinical testing in nine pediatric patients at Ahero and Suba Hospitals. Power was unavailable for 2% of the total time observed due to 11 power outages (median 4.6 min, IQR 3.6-13.0 min) that occurred during treatment with the MPR. Oxygen flowrates remained constant across all 11 power outages. Feedback on the MPR was uniformly positive; all respondents indicated that the MPR was easy to use and provided clinically significant help to their patients.

CONCLUSION

We present a MPR oxygen delivery device that has the potential to mitigate power insecurity and improve the standard of care for hypoxemic pediatric patients in resource-limited settings.

摘要

背景

补充氧气是治疗儿童肺炎的基本治疗方法，但在资源匮乏的环境中通常无法获得，或者由于频繁且持久的停电而不可靠。我们提出了一种新型中压储氧器（MPR），可在停电期间通过电力为儿科患者持续输送氧气。

方法

这是一项观察性病例系列初步研究，评估了一种新型 MPR 设备在资源匮乏的儿科病房中的能力、功效和用户评估。我们在受控的临床前环境中设计和测试了 MPR，在两家肯尼亚农村医院确定了该设备的可行性，并使用标准化问卷寻求用户反馈和满意度。

结果

临床前数据表明，MPR 能够在停电期间保持输送氧气的连续流动，并为模拟患者提供氧气。然后，该 MPR 在 Ahero 和 Suba 医院的 9 名儿科患者中进行了临床测试。在使用 MPR 治疗期间，由于 11 次停电（中位数 4.6 分钟，IQR 3.6-13.0 分钟），总观察时间中有 2%的时间没有电力。在所有 11 次停电期间，氧气流量保持不变。对 MPR 的反馈均为正面；所有受访者都表示，MPR 使用方便，为其患者提供了有临床意义的帮助。