[复发性脑膜炎揭示了宾-尼尔综合征]
[Recurrent meningitis revealing a Bing-Neel syndrome].
作者信息
Sobczak T, Alleman L, Wille H, Menard F, Benard Y, Perard B, Vareil M O
机构信息
Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de la Côte Basque, 13, avenue de l'Interne Jacques Loeb, 64100 Bayonne.
Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de la Côte Basque, 13, avenue de l'Interne Jacques Loeb, 64100 Bayonne.
出版信息
Rev Med Interne. 2021 May;42(5):359-362. doi: 10.1016/j.revmed.2021.02.012. Epub 2021 Mar 2.
INTRODUCTION
Bing-Neel syndrome is a rare complication of Waldenström macroglobulinemia, defined by monoclonal lymphoplasmocytic cells in the cerebrospinal fluid or in central nervous system biopsy.
CASE REPORT
We report a 47-year-old man, with no prior history, who presented a recurrent aseptic lymphocytic meningitis with central nervous manifestations. The presence of a monoclonal lymphoplasmacytic proliferation in cerebrospinal fluid, blood and bone marrow biopsy results was compatible with a diagnosis of Bing-Neel syndrome. Despite the absence of any specific treatment, there was no recurrence of symptoms at 4-month follow-up, and the MRI lesions remained stable.
CONCLUSION
We report a case of Bing-Neel syndrome revealed by a recurrent meningitis. Outcome without treatment was favorable at 4-month follow-up.
引言
宾-尼尔综合征是华氏巨球蛋白血症的一种罕见并发症，其定义为脑脊液或中枢神经系统活检中存在单克隆淋巴细胞浆细胞。
病例报告
我们报告一名47岁男性，既往无病史，出现复发性无菌性淋巴细胞性脑膜炎并伴有中枢神经系统表现。脑脊液、血液和骨髓活检结果显示存在单克隆淋巴细胞浆细胞增殖，符合宾-尼尔综合征的诊断。尽管未进行任何特异性治疗，但在4个月的随访中症状未复发，且磁共振成像（MRI）病变保持稳定。
结论
我们报告一例由复发性脑膜炎发现的宾-尼尔综合征病例。在4个月的随访中，未经治疗的结果良好。
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