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聚-4-羟基丁酸酯补片感染的成功保守治疗:一例报告

Successful conservative treatment of a poly-4-hydroxybutyrate mesh infection: A case report.

作者信息

Lambrecht Maarten, Tollens Tim

机构信息

Department of General Surgery, UZ Leuven, Herestraat 49, 3000, Leuven, Belgium.

Head of Department of Abdominal Surgery, Imelda VZW, Imeldalaan 9, 2820, Bonheiden, Belgium.

出版信息

Ann Med Surg (Lond). 2021 Feb 17;63:102162. doi: 10.1016/j.amsu.2021.02.008. eCollection 2021 Mar.

DOI:10.1016/j.amsu.2021.02.008
PMID:33664948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7905175/
Abstract

INTRODUCTION AND IMPORTANCE

An infection of an abdominal wall prosthesis can be a real disaster for the patient. A conservative treatment might be an option if biological or slowly resorbable synthetic meshes were used. However, adequate research of their use in contaminated and dirty wounds lacks.

CASE PRESENTATION

Herein we report the case of a 69-year-old patient with a heavily infected poly-4-hydroxybutyrate mesh that was successfully treated conservatively.

CLINICAL DISCUSSION

Despite promising results of poly-4-hydroxybutyrate meshes, their use remains controversial and studies in contaminated wounds are scarce.

CONCLUSION

Our case report shows the potential benefits of a poly-4-hydroxybutyrate mesh in a very high-risk patient with active infection.

摘要

引言与重要性

腹壁假体感染对患者而言可能是一场真正的灾难。如果使用生物或可缓慢吸收的合成补片,保守治疗可能是一种选择。然而,目前缺乏对其在污染和不洁伤口中应用的充分研究。

病例报告

在此,我们报告一例69岁患者,其聚-4-羟基丁酸补片严重感染,但通过保守治疗成功治愈。

临床讨论

尽管聚-4-羟基丁酸补片有令人期待的效果,但其应用仍存在争议,且在污染伤口方面的研究较少。

结论

我们的病例报告显示了聚-4-羟基丁酸补片在患有活动性感染的极高风险患者中的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/2b35935d150e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/ce014e2ebf71/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/8c1091057412/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/2b35935d150e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/ce014e2ebf71/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/8c1091057412/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af86/7905175/2b35935d150e/gr3.jpg

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本文引用的文献

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Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
2
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Surg Endosc. 2018 Apr;32(4):1929-1936. doi: 10.1007/s00464-017-5886-1. Epub 2017 Oct 23.
3
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Surg Endosc. 2018 Apr;32(4):1689-1694. doi: 10.1007/s00464-017-5848-7. Epub 2017 Sep 15.
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Characterization of host response, resorption, and strength properties, and performance in the presence of bacteria for fully absorbable biomaterials for soft tissue repair.用于软组织修复的完全可吸收生物材料的宿主反应、吸收、强度特性以及在细菌存在下的性能表征。
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