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Auer rods in mixed phenotype acute leukemia, T/myeloid: A report of three cases.

作者信息

Li Yan, Yang Wenrui, Wang Wei, Lin Dong, Wei Hui, Wang Ying, Liu Bingcheng, Wang Huijun, Xiao Jigang, Ru Yongxin, Dong Shuxu, Wang Jianxiang, Mi Yingchang

机构信息

State Key Laboratory of Experimental Hematology and National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin, China.

Tianjin Key Laboratory of Immunotherapy, Tianjin, China.

出版信息

Leuk Res Rep. 2021 Feb 9;15:100236. doi: 10.1016/j.lrr.2021.100236. eCollection 2021.

DOI:10.1016/j.lrr.2021.100236
PMID:33665079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7902533/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f26/7902533/4c8b28ef751d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f26/7902533/4c8b28ef751d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f26/7902533/4c8b28ef751d/gr1.jpg

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Auer rods in mixed phenotype acute leukemia, T/myeloid: A report of three cases.混合表型急性白血病，T/髓系中的奥厄小体：三例报告
Leuk Res Rep. 2021 Feb 9;15:100236. doi: 10.1016/j.lrr.2021.100236. eCollection 2021.
2
Prognostic significance of Auer rods in childhood acute myelogenous leukemia: results of the studies AML-BFM-78 and -83.奥厄小体在儿童急性髓细胞白血病中的预后意义：AML-BFM-78和-83研究结果
Med Pediatr Oncol. 1989;17(3):202-9. doi: 10.1002/mpo.2950170307.
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[Incidence and prognostic significance of Auer rods in children with acute myeloid leukemia in the studies AML-BFM-78 and -83].[AML-BFM-78和-83研究中急性髓系白血病患儿奥氏小体的发生率及预后意义]
Klin Padiatr. 1989 Jul-Aug;201(4):227-32. doi: 10.1055/s-2007-1025308.
4
Crystal structure of Auer rods in acute myeloblastic leukaemia (AMyL).急性髓细胞白血病（AMyL）中奥氏小体的晶体结构。
J Clin Pathol. 1986 May;39(5):569-72. doi: 10.1136/jcp.39.5.569.
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Acute promyelocytic leukemia with additional chromosomal abnormalities and absence of Auer rods.伴有其他染色体异常且无Auer小体的急性早幼粒细胞白血病
Am J Clin Pathol. 1999 Jul;112(1):113-8. doi: 10.1093/ajcp/112.1.113.
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Low blast count myeloid disorders with Auer rods: a clinicopathologic analysis of 9 cases.伴有奥氏小体的低原始细胞计数髓系疾病：9例临床病理分析
Am J Clin Pathol. 2005 Aug;124(2):191-8. doi: 10.1309/WB79-MFV6-FCDJ-H2EG.
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Comparative study of the efficacy of Wright-Giemsa stain and Liu's stain in the detection of Auer rods in acute promyelocytic leukemia.瑞氏-吉姆萨染色与刘氏染色检测急性早幼粒细胞白血病中Auer小体效能的比较研究
Acta Histochem. 2014 Jul;116(6):1113-6. doi: 10.1016/j.acthis.2014.05.005. Epub 2014 Jun 21.
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Auer rods and myeloperoxidase: an approach for investigating changes at the molecular level in acute myeloid leukaemia (AML).奥氏小体与髓过氧化物酶：一种研究急性髓系白血病（AML）分子水平变化的方法。
Med Hypotheses. 1989 Nov;30(3):175-7. doi: 10.1016/0306-9877(89)90058-3.
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Auer rods in the acute myeloid leukemias: frequency and methods of demonstration.急性髓系白血病中的奥氏小体：出现频率及检测方法
Hematol Oncol. 1987 Jul-Sep;5(3):197-202. doi: 10.1002/hon.2900050306.
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Juvenile myelomonocytic leukemia with t(3;5)(q25;q35), Auer rods and marked myelodysplasia.伴有t(3;5)(q25;q35)、奥氏小体及明显骨髓发育异常的青少年粒单核细胞白血病。
Pathol Res Pract. 2018 Jun;214(6):919-923. doi: 10.1016/j.prp.2017.11.024. Epub 2017 Dec 5.

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Broad genomic workup including optical genome mapping uncovers a : gene fusion in acute myeloid leukemia.包括光学基因组图谱分析在内的广泛基因组检查揭示了急性髓系白血病中的一种基因融合。
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本文引用的文献

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Acute Myeloid Leukemia Expressing T-Cell Antigens: Clinico-Hematological Report on Six Cases.表达T细胞抗原的急性髓系白血病：6例临床血液学报告
Leuk Lymphoma. 1990;3(3):217-22. doi: 10.3109/10428199009050999.
2
Allo-HSCT for acute leukemia of ambiguous lineage in adults: the comparison between standard conditioning and intensified conditioning regimens.成人混合谱系急性白血病的allo-HSCT：标准预处理与强化预处理方案的比较。
Ann Hematol. 2013 May;92(5):679-87. doi: 10.1007/s00277-012-1662-4. Epub 2012 Dec 30.
3
Clinical, immunophenotypic, cytogenetic, and molecular genetic features in 117 adult patients with mixed-phenotype acute leukemia defined by WHO-2008 classification.
117 例 WHO-2008 分类定义的混合表型急性白血病成人患者的临床、免疫表型、细胞遗传学和分子遗传学特征。
Haematologica. 2012 Nov;97(11):1708-12. doi: 10.3324/haematol.2012.064485. Epub 2012 May 11.
4
Mixed-phenotype acute leukemia: historical overview and a new definition.混合表型急性白血病：历史概述与新定义。
Leukemia. 2010 Nov;24(11):1844-51. doi: 10.1038/leu.2010.202. Epub 2010 Sep 16.
5
Acute leukemias of ambiguous lineage: diagnostic consequences of the WHO2008 classification.急性未定系白血病：2008年世界卫生组织分类的诊断结果
Leukemia. 2010 Jul;24(7):1392-6. doi: 10.1038/leu.2010.119. Epub 2010 May 20.
6
Clinical and biological characteristics of adult biphenotypic acute leukemia in comparison with that of acute myeloid leukemia and acute lymphoblastic leukemia: a case series of a Chinese population.成人双表型急性白血病与急性髓系白血病和急性淋巴细胞白血病相比的临床和生物学特征：一组中国人群的病例系列
Haematologica. 2009 Jul;94(7):919-27. doi: 10.3324/haematol.2008.003202. Epub 2009 May 19.
7
Prognostic implications of the immunophenotype in biphenotypic acute leukemia.双表型急性白血病免疫表型的预后意义
Leuk Lymphoma. 2008 Apr;49(4):700-9. doi: 10.1080/10428190701843247.
8
Acute bilineal leukemia: a rare disease with poor outcome.急性双系白血病：一种预后不良的罕见疾病。
Leukemia. 2007 Nov;21(11):2264-70. doi: 10.1038/sj.leu.2404848. Epub 2007 Jul 5.
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An adult case of acute biphenotypic leukemia with characteristic mixed morphology.一例具有特征性混合形态的成人急性双表型白血病病例。
Mo Med. 1993 Sep;90(9):601-4.
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Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).急性白血病免疫分类建议。白血病免疫特征欧洲小组（EGIL）。
Leukemia. 1995 Oct;9(10):1783-6.