van Houten Pepijn, de Rooy Jacky, van der Geest Ingrid, Netea-Maier Romana, van de Ven Annenienke
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.
Bone Rep. 2021 Feb 18;14:100756. doi: 10.1016/j.bonr.2021.100756. eCollection 2021 Jun.
Avascular necrosis of the femoral head is a well-known complication of treatment with high dosage glucocorticoids and has been described in a few patients with Cushing's syndrome. In this case report, we describe the, to our knowledge, first case of a patient with endogenous Cushing's syndrome with a bone infarction located in the distal femur. In patients with Cushing's syndrome and bone pain, the diagnosis of bone infarction should be considered as it can occur as a rare complication of hypercortisolism.
股骨头缺血性坏死是高剂量糖皮质激素治疗的一种众所周知的并发症,并且在少数库欣综合征患者中已有描述。在本病例报告中,据我们所知,我们描述了首例患有内源性库欣综合征且股骨远端发生骨梗死的患者。对于患有库欣综合征且伴有骨痛的患者,应考虑骨梗死的诊断,因为它可能是皮质醇增多症的一种罕见并发症。