Department of Applied Pharmac eutics and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan.
Expert Rev Pharmacoecon Outcomes Res. 2022 Apr;22(3):497-503. doi: 10.1080/14737167.2021.1899814. Epub 2021 Mar 14.
Cost-related nonadherence to medications is a commonly encountered problem posed by many patients, and specifically among elderly patients who use multiple chronic medications. This study aims to explore the prevalence of medication cost-related nonadherence and its predictors in Jordan.
A cross-sectional study was conducted between February 2019 and May 2019 in Jordan. The CRN questionnaire was used as a measure to assess the prevalence of cost-related nonadherence. Logistic regression was used to determine predictors of medication cost-related nonadherence.
The prevalence rate of CRN was 29.6% (95% CI: 27.0-32.3). Participants who are married or widowed were found to have higher odds of being non-adherent due to medication costs, with an odds ratio of 1.55 (95%CI: 1.19-2.00) and 1.95 (95%CI: 1.20-3.15), respectively. Lower educational level was associated with higher odds of being non-adherent 1.95 (95%CI: 1.25-3.05). Being retired was associated with higher odds of being non-adherent (2.20 (95%CI: 1.49-3.27)).
Cost-related nonadherence is a common problem in Jordan and was most prevalent among those with hypertension and diabetes mellitus, low-income, and low levels of education. Our findings could help in developing interventions to improve cost-related medication nonadherence in developing countries.
与药物费用相关的不依从是许多患者普遍存在的问题,尤其是在使用多种慢性药物的老年患者中。本研究旨在探讨约旦药物费用相关不依从的流行率及其预测因素。
2019 年 2 月至 2019 年 5 月在约旦进行了一项横断面研究。CRN 问卷用于评估与费用相关的不依从的流行率。使用逻辑回归来确定药物费用相关不依从的预测因素。
CRN 的流行率为 29.6%(95%CI:27.0-32.3)。已婚或丧偶的参与者由于药物费用而不依从的可能性更高,其比值比分别为 1.55(95%CI:1.19-2.00)和 1.95(95%CI:1.20-3.15)。较低的教育水平与更高的不依从可能性相关,比值比为 1.95(95%CI:1.25-3.05)。退休与更高的不依从可能性相关(比值比为 2.20(95%CI:1.49-3.27))。
与费用相关的不依从在约旦是一个常见问题,在高血压和糖尿病患者、低收入者和受教育程度较低的人群中最为普遍。我们的研究结果可以帮助制定干预措施,以改善发展中国家与费用相关的药物不依从。