Kim Shin Hye, Lee Sang-Yeon, Kim Ji-Soo, Koo Ja-Won
Uijeongbu Eulji Medical Center, Department of Otorhinolaryngology-Head and Neck Surgery, Eulji University College of Medicine, Uijeongbu 11759, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Korea.
J Clin Med. 2021 Feb 13;10(4):756. doi: 10.3390/jcm10040756.
Off-vertical axis rotation (OVAR) is a laboratory test to assess the otolith function. This study aimed to analyze the parameters of OVAR in patients with unilateral vestibular hypofunction (UVH) and bilateral vestibulopathy (BVP), and to correlate the parameters of OVAR with those of VEMPs. Ten healthy volunteers, 41 UVH, and 13 BVP patients performed OVAR. Bias component (BIC) and modulation component (MOC) of UVH and BVP patients were compared with those of healthy controls. BIC and MOC were correlated with amplitude and interaural difference (IAD) of cervical VEMP (cVEMP) and ocular VEMP (oVEMP). In UVH patients, the direction of BICs to affected side rotation were reversed and the absolute value of BICs were decreased when they were compared to healthy controls. In BVP patients, BICs were markedly attenuated. MOCs were not changed in UVH and BVP patients. There was no statistically significant correlation between VEMPs and OVAR.
非垂直轴旋转（OVAR）是一种用于评估耳石功能的实验室检查。本研究旨在分析单侧前庭功能减退（UVH）和双侧前庭病变（BVP）患者的OVAR参数，并将OVAR参数与前庭诱发肌源性电位（VEMP）参数进行相关性分析。10名健康志愿者、41名UVH患者和13名BVP患者进行了OVAR检查。将UVH和BVP患者的偏差分量（BIC）和调制分量（MOC）与健康对照者的进行比较。BIC和MOC与颈肌前庭诱发肌源性电位（cVEMP）和眼肌前庭诱发肌源性电位（oVEMP）的幅值及双耳差值（IAD）进行相关性分析。与健康对照者相比，UVH患者中，BIC指向患侧旋转的方向相反，且BIC的绝对值降低。在BVP患者中，BIC明显减弱。UVH和BVP患者的MOC无变化。VEMP与OVAR之间无统计学显著相关性。
