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多发性骨髓瘤患者脊髓浆细胞瘤导致的脊髓压迫:一例报告

Spinal Cord Compression as a Consequence of Spinal Plasmacytoma in a Patient with Multiple Myeloma: A Case Report.

作者信息

Trivedi Rishi Jayesh

机构信息

Faculty of Medical Sciences, University of Bristol, Bristol BS8 1TH, UK.

出版信息

Clin Pract. 2021 Feb 25;11(1):124-130. doi: 10.3390/clinpract11010018.

DOI:10.3390/clinpract11010018
PMID:33668980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7930977/
Abstract

Multiple myeloma (MM) is a B cell malignancy resulting in osteolytic lesions. Pathological fracture of the vertebral body resulting in spinal cord compression is a common complication and accounts for approximately 5% of patients with MM. To date, there are no definitive guidelines for the treatment of spinal cord compression as a consequence of MM. Radiotherapy has frequently been the preferred form of treatment. Some surgeons, however, feel that spinal lesions in multiple myeloma should be treated in the same manner as spinal metastases from solid organs. I report the management of a 46-year-old gentleman with multiple myeloma that had resulted in neural compression in the lumbar and thoracic areas. Initial emergent treatment in this patient consisted of spinal decompression and stabilisation.

摘要

多发性骨髓瘤(MM)是一种导致溶骨性病变的B细胞恶性肿瘤。椎体病理性骨折导致脊髓受压是一种常见并发症,约占MM患者的5%。迄今为止,对于MM所致脊髓受压的治疗尚无明确指南。放疗一直是常用的治疗方式。然而,一些外科医生认为,多发性骨髓瘤的脊柱病变应与实体器官的脊柱转移瘤采用相同的治疗方式。我报告了一名46岁男性多发性骨髓瘤患者的治疗情况,该患者已导致腰骶部神经受压。该患者最初的紧急治疗包括脊髓减压和固定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/727a8fc93603/clinpract-11-00018-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/390c39a5c9c0/clinpract-11-00018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/34d1734cccd4/clinpract-11-00018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/727a8fc93603/clinpract-11-00018-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/390c39a5c9c0/clinpract-11-00018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/34d1734cccd4/clinpract-11-00018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0519/7930977/727a8fc93603/clinpract-11-00018-g003.jpg

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