Vogl T, Brüning R, Grevers G, Mees K, Bauer M, Lissner J
Department of Radiology, University of Munich, Klinikum Grosshadern, F.R.G.
J Comput Assist Tomogr. 1988 May-Jun;12(3):427-33. doi: 10.1097/00004728-198805010-00014.
The effect of intravenously administered gadolinium-diethylene-triamine pentaacetic acid (Gd-DTPA) on signal intensity in comparison to plain noncontrast imaging was analyzed. Sixty-one patients with diseases of the oropharynx and tongue base were examined using multiplanar magnetic resonance (MR) imaging. The contrast medium Gd-DTPA was administered in 26 cases. Thirty-eight patients also underwent CT. Forty-one patients had surgery and pathological verification. Plain MR imaging was equal or superior to CT in all except one patient. Marked contrast enhancement produced by Gd-DTPA was observed in carcinomas, sarcomas, inflamed salivary glands, and in normal pharyngeal mucosa. The usefulness of Gd-DTPA may be increased by measuring the enhancement in signal intensity versus time to allow a better differentiation of histological features.
分析了静脉注射钆-二乙烯三胺五乙酸（Gd-DTPA）与平扫非增强成像相比对信号强度的影响。使用多平面磁共振（MR）成像检查了61例口咽和舌根疾病患者。26例患者使用了造影剂Gd-DTPA。38例患者还接受了CT检查。41例患者接受了手术及病理验证。除1例患者外，平扫MR成像在所有方面均等同于或优于CT。在癌、肉瘤、炎性唾液腺及正常咽黏膜中观察到Gd-DTPA产生明显的造影剂增强。通过测量信号强度增强与时间的关系，可能会提高Gd-DTPA的效用，以便更好地区分组织学特征。
