Independent Researcher, São Paulo 04029-200, Brazil.
Toxins (Basel). 2021 Feb 18;13(2):159. doi: 10.3390/toxins13020159.
Unilateral peripheral facial nerve palsy jeopardizes quality of life, rendering psychological consequences such as low self-esteem, social isolation, anxiety, and depression. Among therapeutical approaches, use of Botulinum toxin type A (BoNT-A) on the nonparalyzed side has shown promising results and improvement of quality of life. Nevertheless, the correct technique is paramount, since over-injection of the muscles can result in lack of function, leading to a "paralyzed" appearance, and even worse, functional incompetence, which may cause greater distress to patients. Therefore, the objective of this article is to provide a practical guideline for botulinum toxin use in facial palsy. To this aim, adequate patient assessment, BoNT-A choice, injection plan and dosage, and injection techniques are covered.
单侧周围性面神经麻痹会影响生活质量，导致自尊心降低、社交孤立、焦虑和抑郁等心理后果。在治疗方法中，在未麻痹侧使用肉毒毒素 A（BoNT-A）已显示出良好的效果和生活质量的改善。然而，正确的技术至关重要，因为过度注射肌肉可能导致功能丧失，导致“麻痹”外观，甚至更糟的是功能障碍，这可能会给患者带来更大的困扰。因此，本文的目的是为面瘫患者提供肉毒毒素使用的实用指南。为此，涵盖了充分的患者评估、BoNT-A 的选择、注射计划和剂量以及注射技术。
