• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

唾液对口腔念珠菌病的积极作用：唾液特性分析的基础研究

Positive Effects of Saliva on Oral Candidiasis: Basic Research on the Analysis of Salivary Properties.

作者信息

Kawanishi Norishige, Hoshi Noriyuki, Adachi Takuya, Ichigaya Narumi, Kimoto Katsuhiko

机构信息

Department of Oral Interdisciplinary Medicine, Prosthodontics & Oral Implantology, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka 238-8580, Japan.

出版信息

J Clin Med. 2021 Feb 17;10(4):812. doi: 10.3390/jcm10040812.

DOI:10.3390/jcm10040812
PMID:33671369
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7922919/
Abstract

The major causes of oral candidiasis include decreased salivary flow rate and the use of ill-fitting dentures. However, the relationships among prosthetic treatment, saliva, and have not been elucidated. This study aimed to examine the effects of prosthetic treatment and changes in saliva (mainly the salivary flow rate) on oral candidiasis symptoms. Participants requiring prosthetic treatment underwent testing for , salivary flow rate, intraoral symptoms, and bite force at the initial visit and four months after treatment to evaluate pretreatment and post-treatment changes. The relationships among , salivary flow rate, dentures, and intraoral symptoms were analyzed using multiple regression analysis. Denture treatment improved activity against as well as the salivary flow rate, intraoral symptoms, and masticatory function. Multiple regression analysis revealed that changes in the stimulated salivary flow rate due to prosthetic treatment significantly improved detection ( = 0.011), intraoral symptoms ( = 0.037), and bite force ( = 0.031). This study showed that prosthetic treatment improved salivary flow and intraoral symptoms and confirmed the influence of stimulated salivary flow rate changes.

摘要

口腔念珠菌病的主要病因包括唾液流速降低和使用不合适的假牙。然而，修复治疗、唾液之间的关系尚未阐明。本研究旨在探讨修复治疗及唾液变化（主要是唾液流速）对口腔念珠菌病症状的影响。需要修复治疗的参与者在初诊时以及治疗后四个月接受了检测，包括[未提及的某项检测内容]、唾液流速、口腔内症状和咬合力，以评估治疗前后的变化。使用多元回归分析来分析[未提及的某项检测内容]、唾液流速、假牙和口腔内症状之间的关系。假牙治疗改善了对[未提及的某项检测内容]的活性以及唾液流速、口腔内症状和咀嚼功能。多元回归分析显示，修复治疗导致的刺激唾液流速变化显著改善了[未提及的某项检测内容]检测（P = 0.011）、口腔内症状（P = 0.037）和咬合力（P = 0.031）。本研究表明，修复治疗改善了唾液流速和口腔内症状，并证实了刺激唾液流速变化的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/ff09482dae01/jcm-10-00812-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/339cf64f087e/jcm-10-00812-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/d73c15a8dc0c/jcm-10-00812-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/6adb017ca4bd/jcm-10-00812-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/ff09482dae01/jcm-10-00812-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/339cf64f087e/jcm-10-00812-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/d73c15a8dc0c/jcm-10-00812-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/6adb017ca4bd/jcm-10-00812-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc32/7922919/ff09482dae01/jcm-10-00812-g004.jpg

相似文献

1
Positive Effects of Saliva on Oral Candidiasis: Basic Research on the Analysis of Salivary Properties.唾液对口腔念珠菌病的积极作用：唾液特性分析的基础研究
J Clin Med. 2021 Feb 17;10(4):812. doi: 10.3390/jcm10040812.
2
Clinical and histological findings of denture stomatitis as related to intraoral colonization patterns of Candida albicans, salivary flow, and dry mouth.义齿性口炎的临床和组织学发现与白色念珠菌的口腔内定植模式、唾液流率和口干有关。
J Prosthodont. 2013 Jan;22(1):13-22. doi: 10.1111/j.1532-849X.2012.00906.x. Epub 2012 Oct 25.
3
Effects of Denture Treatment on Salivary Metabolites: A Pilot Study.义齿治疗对唾液代谢物的影响：一项初步研究。
Int J Mol Sci. 2023 Sep 11;24(18):13959. doi: 10.3390/ijms241813959.
4
Risk factors related to oral candidiasis in patients with primary Sjögren's syndrome.原发性干燥综合征患者口腔念珠菌病的相关危险因素。
Med Oral Patol Oral Cir Bucal. 2020 Sep 1;25(5):e700-e705. doi: 10.4317/medoral.23719.
5
Differences between salivary and blood neutrophils from elderly and young denture wearers.老年和年轻义齿佩戴者唾液和血液中性粒细胞的差异。
J Oral Rehabil. 2011 Jan;38(1):41-51. doi: 10.1111/j.1365-2842.2010.02126.x.
6
Increase of salivary flow rate along with improved occlusal force after the replacement of complete dentures.全口义齿修复后唾液流速增加以及咬合力改善。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Aug;108(2):211-5. doi: 10.1016/j.tripleo.2009.03.020.
7
A clinical study to compare between resting and stimulated whole salivary flow rate and pH before and after complete denture placement in different age groups.一项比较不同年龄组全口义齿修复前后静息和刺激状态下全唾液流速及pH值的临床研究。
J Indian Prosthodont Soc. 2015 Oct-Dec;15(4):356-66. doi: 10.4103/0972-4052.164907.
8
Mycological and cytological examination of oral candidal carriage in diabetic patients and non-diabetic control subjects: thorough analysis of local aetiologic and systemic factors.糖尿病患者和非糖尿病对照受试者口腔念珠菌携带情况的真菌学和细胞学检查：对局部病因和全身因素的深入分析。
J Oral Rehabil. 2002 May;29(5):452-7. doi: 10.1046/j.1365-2842.2002.00837.x.
9
Oral status and Candida colonization in patients with Sjögren's Syndrome.干燥综合征患者的口腔状况和念珠菌定植。
Med Oral Patol Oral Cir Bucal. 2010 Mar 1;15(2):e310-5. doi: 10.4317/medoral.15.e310.
10
A Preliminary Pilot Study: Metabolomic Analysis of Saliva in Oral Candidiasis.一项初步试点研究：口腔念珠菌病唾液的代谢组学分析。
Metabolites. 2022 Dec 19;12(12):1294. doi: 10.3390/metabo12121294.

引用本文的文献

1
Effects of Denture Treatment on Salivary Metabolites: A Pilot Study.义齿治疗对唾液代谢物的影响：一项初步研究。
Int J Mol Sci. 2023 Sep 11;24(18):13959. doi: 10.3390/ijms241813959.
2
A Preliminary Pilot Study: Metabolomic Analysis of Saliva in Oral Candidiasis.一项初步试点研究：口腔念珠菌病唾液的代谢组学分析。
Metabolites. 2022 Dec 19;12(12):1294. doi: 10.3390/metabo12121294.
3
Editorial of Special Issue "Metabolomic Analysis in Health and Diseases".《“健康与疾病中的代谢组学分析”特刊社论》

本文引用的文献

1
Quantification of Salivary Charged Metabolites using Capillary Electrophoresis Time-of-flight-mass Spectrometry.使用毛细管电泳飞行时间质谱法对唾液带电代谢物进行定量分析。
Bio Protoc. 2020 Oct 20;10(20):e3797. doi: 10.21769/BioProtoc.3797.
2
Salivary metabolomics for cancer detection.唾液代谢组学用于癌症检测。
Expert Rev Proteomics. 2020 Sep;17(9):639-648. doi: 10.1080/14789450.2020.1846524. Epub 2020 Nov 12.
3
Development of a Multiplex PCR Platform for the Rapid Detection of Bacteria, Antibiotic Resistance, and in Human Blood Samples.
J Clin Med. 2021 Aug 7;10(16):3491. doi: 10.3390/jcm10163491.
开发一种用于快速检测人血样本中细菌、抗生素耐药性和 的多重 PCR 平台。
Front Cell Infect Microbiol. 2019 Nov 13;9:389. doi: 10.3389/fcimb.2019.00389. eCollection 2019.
4
Candida coinfection among patients with pulmonary tuberculosis in Asia and Africa; A systematic review and meta-analysis of cross-sectional studies.亚洲和非洲肺结核患者中念珠菌合并感染；横断面研究的系统评价和荟萃分析。
Microb Pathog. 2020 Feb;139:103898. doi: 10.1016/j.micpath.2019.103898. Epub 2019 Nov 30.
5
The effect of overnight storage conditions on complete denture colonization by Candida albicans and dimensional stability: A systematic review.过夜储存条件对白色念珠菌在全口义齿上定殖及尺寸稳定性的影响：一项系统评价
J Prosthet Dent. 2020 Aug;124(2):176-182. doi: 10.1016/j.prosdent.2019.07.014. Epub 2019 Nov 29.
6
The power of saliva: Antimicrobial and beyond.唾液的力量：抗菌及其他作用
PLoS Pathog. 2019 Nov 14;15(11):e1008058. doi: 10.1371/journal.ppat.1008058. eCollection 2019 Nov.
7
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study.纳米金刚石对白色念珠菌黏附及 PMMA 义齿基托材料表面特性的影响——一项体外研究。
J Appl Oral Sci. 2019 Nov 4;27:e20180779. doi: 10.1590/1678-7757-2018-0779. eCollection 2019.
8
Molecular community profiling of the bacterial microbiota associated with denture-related stomatitis.与义齿相关性口炎相关的细菌微生物群落的分子群落分析。
Sci Rep. 2019 Jul 15;9(1):10228. doi: 10.1038/s41598-019-46494-0.
9
Salivary Biomarkers in Denture Stomatitis: A Systematic Review.义齿性口炎中的唾液生物标志物：一项系统综述
JDR Clin Trans Res. 2019 Oct;4(4):312-322. doi: 10.1177/2380084419830941. Epub 2019 Mar 7.
10
Effects of inter-day and intra-day variation on salivary metabolomic profiles.日间和日内变化对唾液代谢组学特征的影响。
Clin Chim Acta. 2019 Feb;489:41-48. doi: 10.1016/j.cca.2018.11.030. Epub 2018 Nov 24.