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在脑-肌肉串扰背景下,中风后肌肉减少症与认知功能障碍是否共病?

Are Sarcopenia and Cognitive Dysfunction Comorbid after Stroke in the Context of Brain-Muscle Crosstalk?

作者信息

Sui Sophia X, Hordacre Brenton, Pasco Julie A

机构信息

IMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, VIC 3220, Australia.

IIMPACT in Health, Allied Health and Human Performance, University of South Australia, Adelaide, SA 5000, Australia.

出版信息

Biomedicines. 2021 Feb 22;9(2):223. doi: 10.3390/biomedicines9020223.

Abstract

Stroke is a leading cause of death and disability and is responsible for a significant economic burden. Sarcopenia and cognitive dysfunction are common consequences of stroke, but there is less awareness of the concurrency of these conditions. In addition, few reviews are available to guide clinicians and researchers on how to approach sarcopenia and cognitive dysfunction as comorbidities after stroke, including how to assess and manage them and implement interventions to improve health outcomes. This review synthesises current knowledge about the relationship between post-stroke sarcopenia and cognitive dysfunction, including the physiological pathways, assessment tools, and interventions involved.

摘要

中风是导致死亡和残疾的主要原因,并且造成了巨大的经济负担。肌肉减少症和认知功能障碍是中风常见的后果,但人们对这些情况同时出现的认识较少。此外,几乎没有综述可供临床医生和研究人员参考,以指导他们如何将肌肉减少症和认知功能障碍作为中风后的合并症来处理,包括如何评估和管理这些合并症以及实施改善健康结局的干预措施。本综述综合了关于中风后肌肉减少症与认知功能障碍之间关系的现有知识,包括其中涉及的生理途径、评估工具和干预措施。

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本文引用的文献

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Obesity and Brain Function: The Brain-Body Crosstalk.肥胖与脑功能:脑-体相互作用
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