Sparks D L, Hunsaker J C
Department of Neurology, University of Kentucky, Medical Center, Lexington 40536-0230.
J Pineal Res. 1988;5(1):111-8. doi: 10.1111/j.1600-079x.1988.tb00773.x.
Sudden infant death syndrome (SIDS) affects infants between 1 month and 1 yr of age, has no known cause, and is diagnosed by exclusion of all other causes of death. The primary mechanism of death in SIDS is considered to be irreversible respiratory cessation during sleep. In a small sampling at necropsy we have observed a statistically significant (P less than .005; determined morphometrically) reduction in the anatomic size of the pineal gland in SIDS infants, as compared to age-matched controls. Whether correspondingly altered pineal glandular function is present in SIDS is as yet unanswered.
婴儿猝死综合征(SIDS)影响1个月至1岁的婴儿,病因不明,通过排除所有其他死亡原因来诊断。SIDS的主要死亡机制被认为是睡眠期间不可逆的呼吸停止。在尸检的一个小样本中,我们观察到与年龄匹配的对照组相比,SIDS婴儿松果体的解剖学尺寸在统计学上有显著减小(P小于0.005;通过形态计量学确定)。SIDS中是否存在相应改变的松果体功能尚未得到解答。