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头间隙的必要性:短头畸形与脑脊液疾病

The Need for Head Space: Brachycephaly and Cerebrospinal Fluid Disorders.

作者信息

Rusbridge Clare, Knowler Penny

机构信息

Faculty of Health & Medical Sciences, School of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.

Fitzpatrick Referrals, Godalming GU7 2QQ, UK.

出版信息

Life (Basel). 2021 Feb 12;11(2):139. doi: 10.3390/life11020139.

Abstract

Brachycephalic dogs remain popular, despite the knowledge that this head conformation is associated with health problems, including airway compromise, ocular disorders, neurological disease, and other co-morbidities. There is increasing evidence that brachycephaly disrupts cerebrospinal fluid movement and absorption, predisposing ventriculomegaly, hydrocephalus, quadrigeminal cistern expansion, Chiari-like malformation, and syringomyelia. In this review, we focus on cerebrospinal fluid physiology and how this is impacted by brachycephaly, airorhynchy, and associated craniosynostosis.

摘要

短头犬仍然很受欢迎,尽管人们知道这种头部形态与健康问题有关,包括气道受阻、眼部疾病、神经疾病和其他合并症。越来越多的证据表明,短头畸形会破坏脑脊液的流动和吸收,易引发脑室扩大、脑积水、四叠体池扩张、 Chiari样畸形和脊髓空洞症。在这篇综述中,我们重点关注脑脊液生理学以及短头畸形、鼻孔狭窄和相关颅缝早闭如何对其产生影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91a/7918167/716e109e4910/life-11-00139-g001.jpg

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