Department of Computer Science and Engineering, Sungkyunkwan University College of Computing, Sungkyunkwan University, 2044 Seobu-ro, Jangan-gu, Suwon, 16419, Republic of Korea.
Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 5 Gil 20, Borame-Road, Dongjak-Gu, Seoul, 07061, Republic of Korea.
Sci Rep. 2021 Mar 5;11(1):5350. doi: 10.1038/s41598-021-84593-z.
Although computer-aided diagnosis (CAD) is used to improve the quality of diagnosis in various medical fields such as mammography and colonography, it is not used in dermatology, where noninvasive screening tests are performed only with the naked eye, and avoidable inaccuracies may exist. This study shows that CAD may also be a viable option in dermatology by presenting a novel method to sequentially combine accurate segmentation and classification models. Given an image of the skin, we decompose the image to normalize and extract high-level features. Using a neural network-based segmentation model to create a segmented map of the image, we then cluster sections of abnormal skin and pass this information to a classification model. We classify each cluster into different common skin diseases using another neural network model. Our segmentation model achieves better performance compared to previous studies, and also achieves a near-perfect sensitivity score in unfavorable conditions. Our classification model is more accurate than a baseline model trained without segmentation, while also being able to classify multiple diseases within a single image. This improved performance may be sufficient to use CAD in the field of dermatology.
虽然计算机辅助诊断(CAD)被用于提高各种医学领域(如乳房 X 线摄影术和结肠镜检查)的诊断质量,但它并未应用于皮肤科,因为皮肤科仅用肉眼进行非侵入性筛查测试,可能存在可避免的错误。本研究通过提出一种新的方法来顺序组合精确的分割和分类模型,表明 CAD 也可能是皮肤科的一种可行选择。给定皮肤图像,我们对图像进行分解以实现标准化并提取高级特征。使用基于神经网络的分割模型创建图像的分割图,然后对异常皮肤的部分进行聚类,并将此信息传递给分类模型。我们使用另一个神经网络模型将每个聚类分类为不同的常见皮肤病。与之前的研究相比,我们的分割模型具有更好的性能,并且在不利条件下也能达到近乎完美的灵敏度评分。我们的分类模型比未经分割训练的基线模型更准确,同时还能够在单个图像中分类多种疾病。这种改进的性能可能足以在皮肤科领域使用 CAD。