姑息性放射治疗对有症状的晚期乳腺癌。

Palliative radiation therapy for symptomatic advance breast cancer.

机构信息

Radiation Oncology, Chaim Sheba Medical Center, Ramat Gan, Israel.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Sci Rep. 2021 Mar 5;11(1):5282. doi: 10.1038/s41598-021-84872-9.

DOI:10.1038/s41598-021-84872-9

PMID:33674709

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7970854/

Abstract

In this study, we evaluated the effectiveness of palliative breast radiation therapy (RT), with single fraction RT compared with fractionated RT. Our study showed that both RT fractionation schemas provide palliation. Single fraction RT allowed for treatment with minimal interference with systemic therapy, whereas fractionated RT provided a more durable palliative response. Due to equivalent palliative response, at our institution we have increasingly been providing single fraction RT palliation during the COVID-19 pandemic.

摘要

在这项研究中，我们评估了姑息性乳房放射治疗 (RT) 的效果，比较了单次分割 RT 与分割 RT。我们的研究表明，两种 RT 分割方案均能提供姑息治疗效果。单次分割 RT 可以在对全身治疗干扰最小的情况下进行治疗，而分割 RT 则提供了更持久的姑息反应。由于姑息反应相当，在 COVID-19 大流行期间，我们医院越来越多地提供单次分割 RT 姑息治疗。