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一名转移性乳腺癌患者在接受大分割放射治疗后,溃疡性肿瘤出现消退。

Regression of a Fungating Tumor After Hypofractionated Radiation Therapy in a Patient With Metastatic Breast Cancer.

作者信息

Quackenbush Kevin, Amini Arya, Fisher Christine M, Rabinovitch Rachel

机构信息

Department of Radiation Oncology, University of Colorado School of Medicine.

出版信息

Cureus. 2017 Jul 2;9(7):e1417. doi: 10.7759/cureus.1417.

DOI:10.7759/cureus.1417
PMID:28875090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5580970/
Abstract

Radiation therapy is a well-established palliative treatment for symptomatic metastases from breast cancer. This is also true of symptomatic primary breast tumors in patients with metastatic disease or in those who are medically inoperable. Further, local progression in the chest wall can severely impair quality of life, with local pain, bleeding, and significant impact on one's self-image. Here, we present the case of a patient who showed an exceptional response to a palliative hypofractionated radiation course to her bleeding, fungating breast primary.

摘要

放射治疗是一种成熟的针对乳腺癌有症状转移灶的姑息治疗方法。对于有转移疾病的患者或因医学原因无法手术的患者中出现症状的原发性乳腺肿瘤,情况也是如此。此外,胸壁局部进展会严重损害生活质量,导致局部疼痛、出血,并对患者自我形象产生重大影响。在此,我们报告一例患者,其对姑息性大分割放疗疗程治疗出血性、溃疡性乳腺原发灶表现出特别的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/e10805a67fa1/cureus-0009-00000001417-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/80798d793bfd/cureus-0009-00000001417-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/7cf20c367435/cureus-0009-00000001417-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/e10805a67fa1/cureus-0009-00000001417-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/80798d793bfd/cureus-0009-00000001417-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/7cf20c367435/cureus-0009-00000001417-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9cb/5580970/e10805a67fa1/cureus-0009-00000001417-i03.jpg

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本文引用的文献

1
Local Treatment of the Primary Tumor in Patients Presenting With Stage IV Breast Cancer: A First, and What's Up Ahead.IV期乳腺癌患者原发肿瘤的局部治疗:首次探索及未来展望。
Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):443-446. doi: 10.1016/j.ijrobp.2016.08.017.
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Cancer Statistics, 2017.《2017 年癌症统计》
CA Cancer J Clin. 2017 Jan;67(1):7-30. doi: 10.3322/caac.21387. Epub 2017 Jan 5.
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Invasive Breast Cancer Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.浸润性乳腺癌,2016年第1版,美国国立综合癌症网络(NCCN)肿瘤学临床实践指南
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Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer: an open-label randomised controlled trial.局部区域治疗与转移性乳腺癌中肿瘤原发灶不治疗的比较:一项开放标签随机对照试验。
Lancet Oncol. 2015 Oct;16(13):1380-8. doi: 10.1016/S1470-2045(15)00135-7. Epub 2015 Sep 9.
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Role of radiation therapy in palliative care of the patient with cancer.放射治疗在癌症患者姑息治疗中的作用。
J Clin Oncol. 2014 Sep 10;32(26):2913-9. doi: 10.1200/JCO.2014.55.1143. Epub 2014 Aug 11.