Kangnam Sacred Heart Hospital, Hallym University College of Medicine.
Konkuk University School of Medicine.
Pain Med. 2021 Jun 4;22(6):1420-1425. doi: 10.1093/pm/pnaa437.
Postdural puncture headache (PDPH) is a potential complication of certain neuraxial anesthesia and spinal procedures, and some risk factors for PDPH have been identified. However, there have been no detailed analyses of rates and risk factors of PDPH after various spinal and neuraxial anesthesia procedures.
Patient data from January 1, 2015, to December 31, 2017, were retrospectively analyzed. The patients underwent dural puncture procedures (spinal anesthesia, lumbar puncture [spinal tap], lumbar cerebrospinal fluid [CSF] drainage) or nondural puncture procedures (transforaminal epidural injection, interlaminar epidural injection, epidural catheterization with patient-controlled analgesia for delivery). PDPH incidence and risk factors were evaluated.
For dural puncture procedures, PDPH incidence was 2.96%, and risk factors were younger age, female sex, and lumbar puncture. Larger needle gauge was a risk factor according to Student t-test but not during logistic regression analysis. PDPH incidence was higher after lumbar puncture using a 22 G Tuohy needle (4.63%) than after lumbar CSF drainage using an 18 G Tuohy needle (3.05%). For nondural puncture procedures, PDPH incidence was 0.53% and did not differ between procedure types; no risk factors were identified.
PDPH incidence and risk factors depended on the type of neuraxial anesthesia and spinal procedures. PDPH incidence after lumbar puncture using a 22 G Tuohy needle was higher than that after lumbar CSF drainage using an 18 G Tuohy needle, suggesting that catheter insertion may reduce PDPH risk. In non-dural puncture procedures, PDPH risk did not differ according to type of procedure, and no risk factors were found.
硬脊膜穿剌后头痛(PDPH)是某些神经轴麻醉和脊髓程序的潜在并发症,并且已经确定了 PDPH 的一些危险因素。然而,对于各种脊髓和神经轴麻醉程序后 PDPH 的发生率和危险因素尚未进行详细分析。
回顾性分析 2015 年 1 月 1 日至 2017 年 12 月 31 日期间的患者数据。患者行硬脊膜穿剌操作(脊髓麻醉、腰椎穿刺[腰穿]、腰椎脑脊液[CSF]引流)或非硬脊膜穿剌操作(经椎间孔硬膜外注射、经椎板间硬膜外注射、分娩时行患者自控镇痛的硬膜外导管置管)。评估 PDPH 的发生率和危险因素。
对于硬脊膜穿剌操作,PDPH 的发生率为 2.96%,危险因素为年龄较小、女性和腰椎穿刺。根据学生 t 检验,较大的针号是危险因素,但在逻辑回归分析中不是。使用 22G Tuohy 针行腰穿时 PDPH 的发生率(4.63%)高于使用 18G Tuohy 针行腰椎 CSF 引流时的发生率(3.05%)。对于非硬脊膜穿剌操作,PDPH 的发生率为 0.53%,不同操作类型之间无差异;未确定危险因素。
PDPH 的发生率和危险因素取决于神经轴麻醉和脊髓操作的类型。使用 22G Tuohy 针行腰穿时 PDPH 的发生率高于使用 18G Tuohy 针行腰椎 CSF 引流时的发生率,提示导管插入可能降低 PDPH 的风险。在非硬脊膜穿剌操作中,根据操作类型,PDPH 的风险无差异,且未发现危险因素。