Liyanage Achala, Liyanage G, De Silva V, Akarawita J, Gunasekera C, Imafuku S, Lekamwasam S
Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Dermatology Department, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Arch Dermatol Res. 2022 Jan;314(1):61-69. doi: 10.1007/s00403-021-02210-5. Epub 2021 Mar 6.
INTRODUCTION/OBJECTIVES: Psoriasis is a chronic inflammatory dermatosis with significant physical and psychological impact leading to negative influence on the quality of life among patients with psoriasis. Other than the disease characteristics many external factors could operate in South Asian context. Lack of a reliable disease-specific instrument prevents objective estimation and monitoring of disability in patients with psoriasis and hence we aim to validate assess the psychometric properties of the Sinhala version of PDI.
A cross-sectional study conducted at dermatology clinic at a tertiary care National Hospital in Sri Lanka. Patients with psoriasis and on therapy at least 4 weeks prior to enrollment, aged more than 18 years, were included while those with already diagnosed psoriatic arthritis and/or nail psoriasis alone without any skin involvement and generalized pustular psoriasis de novo were excluded. All patients were examined by dermatologist to obtain disease characteristics. The reliability was assessed by internal consistency using Cronbach's α and item-total correlation. Convergent validity was measured with the known groups.
Of 199 patients studied, the PDI Sinhala version showed Cronbach's α of 0.86 (all 15 items) and ranged from 0.57 to 0.77 for subscales. PDI score and Dermatology Life Quality Index (DLQI) showed good correlation of coefficient 0.76 (p < 0.01). Positive associations were noted with extent and severity of psoriasis when using sample medians (p < 0.05). The dimensionality of the PDI was determined using exploratory factor analysis and four factors were structured.
The PDI Sinhala version is proved to be valid and reliable tool to assess the burden of psoriasis among Sinhala conversant patients in Sri Lanka.
引言/目的：银屑病是一种慢性炎症性皮肤病，对患者的身体和心理有重大影响，会对银屑病患者的生活质量产生负面影响。除了疾病特征外，在南亚背景下还有许多外部因素起作用。缺乏可靠的疾病特异性工具会妨碍对银屑病患者残疾情况的客观评估和监测，因此我们旨在验证评估僧伽罗语版银屑病残疾指数（PDI）的心理测量特性。
在斯里兰卡一家三级护理国立医院的皮肤科诊所进行了一项横断面研究。纳入了患有银屑病且在入组前至少接受4周治疗、年龄超过18岁的患者，而那些已确诊银屑病关节炎和/或仅患有指甲银屑病而无任何皮肤受累以及新发泛发性脓疱型银屑病的患者被排除。所有患者均由皮肤科医生进行检查以获取疾病特征。通过使用Cronbach's α和项目-总分相关性进行内部一致性评估可靠性。用已知组测量收敛效度。
在研究的199例患者中，僧伽罗语版PDI的Cronbach's α为0.86（所有15个项目），各子量表范围为0.57至0.77。PDI评分与皮肤病生活质量指数（DLQI）显示出良好的相关性，系数为0.76（p < 0.01）。使用样本中位数时，与银屑病的范围和严重程度呈正相关（p < 0.05）。使用探索性因子分析确定了PDI的维度，并构建了四个因子。
僧伽罗语版PDI被证明是评估斯里兰卡说僧伽罗语患者中银屑病负担的有效且可靠的工具。
