United States Department of Veterans Affairs National Center for PTSD, USA; VA Connecticut Healthcare System, West Haven, CT, USA; Yale University School of Medicine, New Haven, CT, USA.
San Diego State University/UC San Diego, San Diego, CA, USA; VA San Diego Healthcare System, San Diego, CA, USA.
J Psychiatr Res. 2021 May;137:104-110. doi: 10.1016/j.jpsychires.2021.02.022. Epub 2021 Feb 14.
A growing body of evidence has shown consistent support for the association between trauma-related guilt and posttraumatic stress disorder (PTSD). However, factors that account for this association are not well understood. The present study examined psychological inflexibility as a potential mediator between trauma-related guilt and PTSD symptoms in a sample of U.S. military veterans. Secondary data analyses from a larger randomized control trial were conducted. Specifically, three separate mediation models were used to test if psychological inflexibility mediated the association between trauma-related guilt (guilt cognitions, guilt distress, overall guilt) and PTSD symptoms in 85 treatment-seeking veterans diagnosed with PTSD and alcohol use disorder. All three components of trauma-related guilt were positively associated with both psychological inflexibility and PTSD symptoms; psychological inflexibility was also positively associated with PTSD symptoms. Furthermore, psychological inflexibility partially mediated the association between all facets of trauma-related guilt and PTSD severity. These findings provide further support for the association between trauma-related guilt and PTSD and also provide insight into one mechanism linking trauma-related guilt to PTSD symptoms. Thus, psychological inflexibility may serve as an important intervention target for veterans with comorbid PTSD and alcohol use disorder struggling with trauma-related guilt.
越来越多的证据表明,创伤后相关内疚与创伤后应激障碍(PTSD)之间存在一致的关联。然而,导致这种关联的因素尚不清楚。本研究在美国退伍军人样本中检验了心理不灵活性作为创伤后相关内疚与 PTSD 症状之间的潜在中介因素。对一项更大的随机对照试验的二次数据分析进行了研究。具体来说,使用了三个单独的中介模型来检验心理不灵活性是否在创伤后相关内疚(内疚认知、内疚痛苦、整体内疚)和 PTSD 症状之间中介,共有 85 名寻求治疗的 PTSD 和酒精使用障碍诊断的退伍军人。创伤后相关内疚的所有三个组成部分都与心理不灵活性和 PTSD 症状呈正相关;心理不灵活性也与 PTSD 症状呈正相关。此外,心理不灵活性部分中介了创伤后相关内疚的所有方面与 PTSD 严重程度之间的关联。这些发现进一步支持了创伤后相关内疚与 PTSD 之间的关联,也为将创伤后相关内疚与 PTSD 症状联系起来的一种机制提供了深入了解。因此,心理不灵活性可能是同时患有 PTSD 和酒精使用障碍且受创伤后相关内疚困扰的退伍军人的一个重要干预目标。