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阅读障碍(诵读困难)的最新研究进展聚焦于神经生物学。

Recent update on reading disability (dyslexia) focused on neurobiology.

作者信息

Kim Sung Koo

机构信息

Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.

出版信息

Clin Exp Pediatr. 2021 Oct;64(10):497-503. doi: 10.3345/cep.2020.01543. Epub 2021 Mar 2.

Abstract

Reading disability (dyslexia) refers to an unexpected difficulty with reading for an individual who has the intelligence to be a much better reader. Dyslexia is most commonly caused by a difficulty in phonological processing (the appreciation of the individual sounds of spoken language), which affects the ability of an individual to speak, read, and spell. In this paper, I describe reading disabilities by focusing on their underlying neurobiological mechanisms. Neurobiological studies using functional brain imaging have uncovered the reading pathways, brain regions involved in reading, and neurobiological abnormalities of dyslexia. The reading pathway is in the order of visual analysis, letter recognition, word recognition, meaning (semantics), phonological processing, and speech production. According to functional neuroimaging studies, the important areas of the brain related to reading include the inferior frontal cortex (Broca's area), the midtemporal lobe region, the inferior parieto-temporal area, and the left occipitotemporal region (visual word form area). Interventions for dyslexia can affect reading ability by causing changes in brain function and structure. An accurate diagnosis and timely specialized intervention are important in children with dyslexia. In cases in which national infant development screening tests have been conducted, as in Korea, if language developmental delay and early predictors of dyslexia are detected, careful observation of the progression to dyslexia and early intervention should be made.

摘要

阅读障碍(诵读困难)是指对于一个智力水平足以成为更好读者的个体而言,其在阅读方面出现的意外困难。诵读困难最常见的原因是语音处理方面的困难(对口语中单个音素的感知),这会影响个体的说话、阅读和拼写能力。在本文中,我将通过关注阅读障碍潜在的神经生物学机制来描述它。使用功能性脑成像的神经生物学研究已经揭示了阅读通路、参与阅读的脑区以及诵读困难的神经生物学异常情况。阅读通路依次为视觉分析、字母识别、单词识别、语义(语义学)、语音处理和言语产生。根据功能性神经成像研究,大脑中与阅读相关的重要区域包括额下回(布洛卡区)、颞中叶区域、顶颞下区域以及左枕颞区域(视觉词形区)。针对诵读困难的干预措施可以通过引起脑功能和结构的变化来影响阅读能力。对于患有诵读困难的儿童来说,准确的诊断和及时的专业干预非常重要。在像韩国那样已经开展全国性婴儿发育筛查测试的情况下,如果检测到语言发育迟缓以及诵读困难的早期预测指标,就应该仔细观察其向诵读困难发展的进程并进行早期干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089a/8498014/3c6440aefdae/cep-2020-01543f1.jpg

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