Department of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Viterbo, Italy.
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Nat Prod Res. 2022 Mar;36(6):1648-1652. doi: 10.1080/14786419.2021.1896512. Epub 2021 Mar 7.
Hydroalcoholic extracts obtained from buds of , and were characterized by HPLC-DAD-MS analysis and subsequently evaluated for their antioxidant and anti-inflammatory activities. ABTS and DPPH assays evidenced that showed the best antioxidant activity in line with its highest total phenolic content. The analysis of the anti-inflammatory activity clearly demonstrated that all extracts suppressed the production of key pro-inflammatory cytokines (IL-6, Il-1β and TNF-α) and HMGB1 inflammatory danger signal. These results show antioxidant and critical anti-inflammatory activities mediated by the extracts, emphasising their potentiality as therapeutic agents.
从 、 和 的芽中提取的水醇提取物通过 HPLC-DAD-MS 分析进行了表征，随后评估了它们的抗氧化和抗炎活性。ABTS 和 DPPH 测定表明， 表现出最好的抗氧化活性，与其最高的总酚含量一致。抗炎活性分析清楚地表明，所有提取物均抑制关键促炎细胞因子（IL-6、Il-1β 和 TNF-α）和 HMGB1 炎症危险信号的产生。这些结果表明提取物具有抗氧化和关键抗炎活性，强调了它们作为治疗剂的潜力。
