Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Jan 28;46(1):84-90. doi: 10.11817/j.issn.1672-7347.2021.200448.
With the advancement of disease treatments, the number of patients undergoing surgery worldwide is increasing. However, many patients still experience severe perioperative complications. Perioperative hypotension is one of the common side effects during surgery. Physiologically, perioperative hypotension can lead to insufficient perfusion of important organs and result in acute and chronic irreversible organ injury, which cause serious consequences for the patient's postoperative hospitalization and even the long-term outcome. Therefore, in order to optimize perioperative circulation management and improve the quality of life for patients after surgery, it is of great importance to investigate the relationship between perioperative hypotension and postoperative myocardial injury, ischemic stroke, postoperative delirium, acute kidney injury, and postoperative mortality. Individualized circulation management and reasonable application of vasoactive drugs may be the key point to early prevention and correct treatment of perioperative hypotension, which is of great significance for reducing perioperative related morbidity and mortality and improving the prognosis for the surgical patients.
随着疾病治疗的进步,全球接受手术的患者数量正在增加。然而,许多患者仍然经历严重的围手术期并发症。围手术期低血压是手术期间常见的副作用之一。从生理学上讲,围手术期低血压会导致重要器官灌注不足,导致急性和慢性不可逆转的器官损伤,这会给患者术后住院甚至长期预后带来严重后果。因此,为了优化围手术期循环管理并提高患者术后的生活质量,研究围手术期低血压与术后心肌损伤、缺血性脑卒中、术后谵妄、急性肾损伤和术后死亡率之间的关系非常重要。个体化循环管理和合理应用血管活性药物可能是早期预防和正确治疗围手术期低血压的关键,这对于降低围手术期相关发病率和死亡率以及改善手术患者的预后具有重要意义。