Ruiz Richard, Cox Thomas, McKenna Gregory J, Onaca Nicholas, Testa Giuliano, Fernandez Hoylan, Bayer Johanna, Wall Anji, Martinez Eric, Gupta Amar, DiNubila J Michelle, Jennings Nicole, Wicklund Kari
Department of Transplant Surgery, Simmons Transplant Institute, Baylor Scott & White All Saints Medical Center, Fort Worth, Texas.
Department of Transplant Surgery, Simmons Transplant Institute, Baylor University Medical Center, Dallas, Texas.
Proc (Bayl Univ Med Cent). 2020 Dec 18;34(2):237-241. doi: 10.1080/08998280.2020.1852835.
Although post-kidney transplant (KT) wound complications are associated with elevated body mass index (BMI), BMI is not an accurate surrogate of obesity. On the other hand, subcutaneous depth (SQD) measurement is a direct marker of truncal obesity. We examined outcomes of differing intraoperative SQD measurements in 113 KT-only recipients over 20 months. Recipients' median age was 51 years; median BMI, 28 kg/m; and mean SQD, 2.9 cm. Patients were stratified into groups of SQD ≤2.5 cm, >2.5-5 cm, and >5 cm. An SQD of >2.5 to 5 cm correlated with a BMI of 30 kg/m (obesity) and an SQD >5 cm correlated with a BMI >35 kg/m (severe obesity). Degree of SQD was not associated with more frequent technical complications such as fascial dehiscence, lymphocele formation, renal artery thrombosis/stenosis, urine leak, or ureteral stenosis. However, an SQD >2.5 cm was a risk factor for requiring a wound vacuum-assisted closure device. There was no difference in graft or patient survival among the three SQD groups. Obesity, as measured directly by SQD, was not associated with increased technical complications or poor outcomes after KT. As expected, there was a higher incidence of wound complications in the higher SQD groups requiring intervention.
尽管肾移植(KT)术后伤口并发症与体重指数(BMI)升高有关,但BMI并非肥胖的准确替代指标。另一方面,皮下深度(SQD)测量是躯干肥胖的直接标志。我们在20个月内对113例仅接受KT的受者术中不同的SQD测量结果进行了研究。受者的中位年龄为51岁;中位BMI为28kg/m;平均SQD为2.9cm。患者被分为SQD≤2.5cm、>2.5至5cm和>5cm三组。SQD>2.5至5cm与BMI为30kg/m(肥胖)相关联,而SQD>5cm与BMI>35kg/m(重度肥胖)相关联。SQD程度与诸如筋膜裂开、淋巴囊肿形成、肾动脉血栓形成/狭窄、尿漏或输尿管狭窄等更频繁的技术并发症无关。然而,SQD>2.5cm是需要伤口真空辅助闭合装置的一个危险因素。三个SQD组之间的移植物或患者生存率没有差异。通过SQD直接测量的肥胖与KT术后技术并发症增加或不良结局无关。正如预期的那样,较高SQD组中需要干预的伤口并发症发生率更高。