Shrestha Badri Man
Badri Man Shrestha, Sheffield Kidney Institute, Sheffield Teaching Hospitals NHS Trust, Sheffield S5 7AU, United Kingdom.
World J Transplant. 2016 Dec 24;6(4):767-773. doi: 10.5500/wjt.v6.i4.767.
To review negative pressure wound therapy (NPWT) as an important addition to the conventional methods of wound management.
A systematic review, performed by searching the PubMed, EMBASE and Cochrane Library databases, showed 11 case reports comprising a total of 22 kidney transplantation (KT) patients (range, 1 to 9), who were treated with NPWT. Application of NPWT was associated with successful healing of wounds, leg ulcer, lymphocele and urine leak from ileal conduit.
No complications related to NPWT were reported. However, there was paucity of robust data on the effectiveness of NPWT in KT recipients; therefore, prospective studies assessing its safety and efficacy of NPWT and randomised trials comparing the effectiveness of NPWT with alternative modalities of wound management in KT recipients is recommended.
Negative pressure incision management system, NPWT with instillation and endoscopic vacuum-assisted closure system are in investigational stage.
回顾负压伤口治疗（NPWT）作为伤口管理传统方法的重要补充。
通过检索PubMed、EMBASE和Cochrane图书馆数据库进行的系统评价显示，有11例病例报告，共22例肾移植（KT）患者（范围为1至9例）接受了NPWT治疗。NPWT的应用与伤口、腿部溃疡、淋巴囊肿和回肠导管尿液漏的成功愈合相关。
未报告与NPWT相关的并发症。然而，关于NPWT在KT受者中的有效性的可靠数据较少；因此，建议进行前瞻性研究以评估NPWT的安全性和有效性，并进行随机试验以比较NPWT与KT受者伤口管理替代方式的有效性。
负压切口管理系统、带灌注的NPWT和内镜下真空辅助闭合系统正处于研究阶段。
