Vinan-Vega Myrian, Mantilla Barbara, Jahan Nusrat, Peminda Cabandugama, Nugent Kenneth, Lado-Abeal Joaquin, Rivas Ana
Division of Internal Medicine/Endocrinology, Texas Tech University Health Science Center, Lubbock, Texas.
Division of Hematology, Texas Tech University Health Science Center, Lubbock, Texas.
Proc (Bayl Univ Med Cent). 2020 Dec 14;34(2):279-282. doi: 10.1080/08998280.2020.1852007.
The standard treatment of complicated thyrotoxicosis and thyroid storm with the concomitant use of antithyroid medication, iodine, beta-blockers, and corticosteroids is successful in most cases. However, treatment options are limited when antithyroidal drugs cannot be used or in cases that are refractory to standard treatment. Plasmapheresis provides a safe and effective strategy when initial treatment fails, facilitating the transition to definitive treatments such as thyroidectomy. We present two adults with complicated thyrotoxicosis successfully treated with plasmapheresis as a bridge therapy to thyroidectomy or as an alternative to drug-induced toxicity.
在大多数情况下，联合使用抗甲状腺药物、碘剂、β受体阻滞剂和皮质类固醇对复杂甲状腺毒症和甲状腺危象进行标准治疗是成功的。然而，当无法使用抗甲状腺药物或对标准治疗无效时，治疗选择就会受到限制。当初始治疗失败时，血浆置换提供了一种安全有效的策略，有助于向甲状腺切除术等确定性治疗过渡。我们报告了两名患有复杂甲状腺毒症的成人患者，他们成功地接受了血浆置换治疗，作为甲状腺切除术的桥接治疗或药物诱导毒性的替代治疗。
