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埃塞俄比亚西北部巴赫达尔市公立医院伤口愈合结果中的营养不良:一项前瞻性队列研究。

Malnutrition in the Outcome of Wound Healing at Public Hospitals in Bahir Dar City, Northwest Ethiopia: A Prospective Cohort Study.

作者信息

Fentahun Netsanet, Anteneh Yeabsira, Menber Yonatan

机构信息

Department of Nutrition and Dietetics, School of Public Health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.

Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.

出版信息

J Nutr Metab. 2021 Feb 18;2021:8824951. doi: 10.1155/2021/8824951. eCollection 2021.

Abstract

BACKGROUND

Poor nutritional status affects the normal process of the wound healing stage. There is limited evidence regarding the association between malnutrition and wound healing in Ethiopia.

OBJECTIVE

To assess the association between nutritional status and wound healing progress among adult individuals who had undergone abdominal surgery at Public Hospitals, Ethiopia.

METHODS

A prospective cohort study was conducted on 310 adult patients who had undergone abdominal surgery from August to December 2019. Data were collected using a standardized, structured, and pretested questionnaire. Anthropometric and serum albumin measurements were used to measure nutritional status. A multivariable Cox-regression analyses model was fitted to show the association between malnutrition and wound healing and value < 0.05 was used to declare statistical significance value.

RESULTS

The cumulative incidence rate of good wound healing was 65.5% (95% CI: 60.0-71.0). Patients who had normal preoperative body mass index (adjusted hazard ratio (AHR) = 2.22 (95% CI: 1.55-3.19)) and normal range of serum albumin level (≥3.5) (AHR = 1.56 (95% CI: 1.05-2.29)) were significantly associated with better wound healing outcomes.

CONCLUSION

Nutritional status had a strong association with good wound healing outcomes. Therefore, nutritional status screening should be done for all adult patients before undergoing abdominal surgery to improve wound healing outcomes and reduce hospital stays.

摘要

背景

营养状况不佳会影响伤口愈合阶段的正常进程。在埃塞俄比亚,关于营养不良与伤口愈合之间关联的证据有限。

目的

评估埃塞俄比亚公立医院接受腹部手术的成年个体营养状况与伤口愈合进程之间的关联。

方法

对2019年8月至12月接受腹部手术的310例成年患者进行前瞻性队列研究。使用标准化、结构化且经过预测试的问卷收集数据。采用人体测量和血清白蛋白测量来评估营养状况。采用多变量Cox回归分析模型来显示营养不良与伤口愈合之间的关联,P值<0.05被用于判定统计学显著性。

结果

伤口愈合良好的累积发生率为65.5%(95%CI:60.0 - 71.0)。术前体重指数正常(调整后风险比(AHR)= 2.22(95%CI:1.55 - 3.19))以及血清白蛋白水平在正常范围(≥3.5)(AHR = 1.56(95%CI:1.05 - 2.29))的患者与更好的伤口愈合结果显著相关。

结论

营养状况与良好的伤口愈合结果密切相关。因此,所有成年患者在接受腹部手术前都应进行营养状况筛查,以改善伤口愈合结果并缩短住院时间。

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