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丘脑梗死:临床综合征、病因及预后

Thalamic infarcts: clinical syndromes, etiology, and prognosis.

作者信息

Bogousslavsky J, Regli F, Uske A

机构信息

Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

出版信息

Neurology. 1988 Jun;38(6):837-48. doi: 10.1212/wnl.38.6.837.

DOI:10.1212/wnl.38.6.837
PMID:3368064
Abstract

We studied forty patients with CT-proven thalamic infarcts without involvement of the superficial territory of the posterior cerebral artery. The delineation into four arterial thalamic territories (inferolateral, tuberothalamic, posterior choroidal, paramedian) corresponded clinically to four different syndromes. The most common etiologies were lacunar infarction, large artery atherosclerosis with presumed artery-to-artery embolism, cardioembolism, and migrainous stroke. We found no risk factor other than age or oral contraceptive use in six patients. One patient died in the acute phase. During follow-up (45.6 months), the stroke or death rate was 7.4% per year. Delayed pain developed in three patients and abnormal movements in three. Late disability was mainly secondary to persisting neuropsychological dysfunction (thalamic dementia).

摘要

我们研究了40例经CT证实的丘脑梗死患者,这些患者的大脑后动脉浅表区域未受累。将丘脑划分为四个动脉区域(下外侧、结节丘脑、脉络膜后、旁正中)在临床上对应四种不同的综合征。最常见的病因是腔隙性梗死、伴有动脉到动脉栓塞的大动脉粥样硬化、心源性栓塞和偏头痛性卒中。我们发现除年龄或6例患者使用口服避孕药外,没有其他危险因素。1例患者在急性期死亡。在随访期间(45.6个月),每年的卒中或死亡率为7.4%。3例患者出现延迟性疼痛,3例出现异常运动。晚期残疾主要继发于持续的神经心理功能障碍(丘脑痴呆)。

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