Withers Jacquelyn A, Lalchandani Gopal R, Halvorson Ryan T, Immerman Igor, Rahgozar Paymon
Division of Plastic and Reconstructive Surgery, University of California, San Francisco, Calif.
Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, Calif.
Plast Reconstr Surg Glob Open. 2021 Feb 16;9(2):e3399. doi: 10.1097/GOX.0000000000003399. eCollection 2021 Feb.
Open (OCTR) and endoscopic carpal tunnel release (ECTR) are both effective treatments for carpal tunnel syndrome, with similar outcomes and complication rates. Given the opioid epidemic, it is important to consider how surgical modality impacts narcotic use. We compared narcotic use after OCTR and ECTR to identify trends and risk factors for prolonged postoperative use.
We utilized the PearlDiver database to identify patients who underwent OCTR and ECTR between 2008 and 2015. Patients with opioid use were analyzed for trends. Early refills, prolonged postoperative opioid use, and new persistent opioid use were defined by time periods relating to the date of surgery. Age, gender, Charlson comorbidity index (CCI), and surgery type (open versus endoscopic) were analyzed as predictors for opioid use.
A total of 29,583 patients were included: 4125 (14%) ECTR and 25,458 (86%) OCTR. Significantly more OCTR patients filled perioperative prescriptions (62% versus 60%), and the OCTR group filled higher quantities of perioperative opioids (411 OME versus 379 OME). Patients in the OCTR group were also significantly more likely to obtain early refills and to have prolonged postoperative use. There was no difference in the rate of new persistent use.
Compared with ECTR, patients who underwent OCTR filled higher quantities of opioids in the perioperative period, were more likely to obtain early refills, and were more likely to have prolonged postoperative use. These findings suggest either a lower opioid requirement after ECTR or a lower perceived requirement reflected in the difference in prescribing habits between techniques.
开放性腕管减压术(OCTR)和内镜下腕管减压术(ECTR)都是治疗腕管综合征的有效方法,疗效和并发症发生率相似。鉴于阿片类药物泛滥,考虑手术方式如何影响麻醉药物使用很重要。我们比较了OCTR和ECTR术后的麻醉药物使用情况,以确定术后长期使用的趋势和风险因素。
我们利用PearlDiver数据库识别2008年至2015年间接受OCTR和ECTR的患者。对使用阿片类药物的患者进行趋势分析。早期再填充、术后长期使用阿片类药物和新的持续性阿片类药物使用是根据与手术日期相关的时间段来定义的。将年龄、性别、Charlson合并症指数(CCI)和手术类型(开放手术与内镜手术)作为阿片类药物使用的预测因素进行分析。
共纳入29583例患者:4125例(14%)接受ECTR,25458例(86%)接受OCTR。接受OCTR的患者围手术期开具处方的比例显著更高(62%对60%),且OCTR组围手术期阿片类药物的开具量更高(411口服吗啡当量对379口服吗啡当量)。OCTR组的患者也显著更有可能进行早期再填充并术后长期使用。新的持续性使用发生率没有差异。
与ECTR相比,接受OCTR的患者围手术期阿片类药物的开具量更高,更有可能进行早期再填充,且更有可能术后长期使用。这些发现表明,要么ECTR术后对阿片类药物的需求量较低,要么技术之间处方习惯的差异反映出较低的感知需求量。