Uyulmaz Semra, Planegger Andrea, Grünherz Lisanne, Giovanoli Pietro, Lindenblatt Nicole
Department of Plastic and Hand Surgery, University Hospital Zurich, Switzerland.
Plast Reconstr Surg Glob Open. 2021 Feb 18;9(2):e3407. doi: 10.1097/GOX.0000000000003407. eCollection 2021 Feb.
Numerous approaches have been employed to treat chronic lymphocele and cutaneous lymphatic fistulas (LFs) with little success. Given a high incidence and substantial consequences for patients, there is an ongoing demand for effective therapeutic and preventive strategies. The aim of this study was to evaluate the results after microscopic lymphatic ligation (MLL) and lymphovenous anastomosis (LVA) as a therapeutic and preventive approach in this context.
Demographic data, surgical characteristics, complications, and the overall outcome of all patients undergoing surgery for postoperative LF from 2014 to 2019 were collected retrospectively. Patients were categorized in accordance with predefined inclusion/exclusion criteria and with their treatment. Statistical analysis was conducted using descriptive, summary statistics to identify a central tendency.
Thirty-four patients underwent indocyanine-green-lymphangiography guided revision surgery for LF. Two patients were lost to follow-up at 6 months. LF was successfully treated in all patients (n = 32) with a multimodal approach. Only MLL was performed in 22 patients and MLL/LVA in 10 patients. LF resolved in 78% of all patients with MLL only or MLL/LVA. In the remaining 22%, LF resolved after additional sclerotherapy within 3 months.
Treatment of LF should follow a standardized staged surgical approach to optimize outcome. LF was treated successfully in all our patients. We therefore propose a multimodal interdisciplinary approach to this common clinical problem that includes adjunctive sclerotherapy.
已采用多种方法治疗慢性淋巴囊肿和皮肤淋巴管瘘(LFs),但收效甚微。鉴于其高发病率以及对患者造成的严重后果,对有效治疗和预防策略的需求一直存在。本研究的目的是评估在这种情况下,显微淋巴管结扎术(MLL)和淋巴管静脉吻合术(LVA)作为一种治疗和预防方法的效果。
回顾性收集2014年至2019年所有因术后LF接受手术治疗患者的人口统计学数据、手术特征、并发症及总体结果。根据预先定义的纳入/排除标准及治疗方法对患者进行分类。采用描述性汇总统计进行统计分析以确定集中趋势。
34例患者接受了吲哚菁绿淋巴管造影引导下的LF修复手术。2例患者在6个月时失访。所有患者(n = 32)均采用多模式方法成功治疗LF。仅22例患者进行了MLL,10例患者进行了MLL/LVA。仅接受MLL或MLL/LVA治疗的所有患者中,78%的患者LF得到解决。其余22%的患者在3个月内通过额外的硬化治疗后LF得到解决。
LF的治疗应遵循标准化的分期手术方法以优化治疗效果。我们所有患者的LF均得到成功治疗。因此,我们针对这一常见临床问题提出一种多模式跨学科方法,包括辅助硬化治疗。