S-羧甲基半胱氨酸治疗胶耳：一项双盲试验

S-carboxymethylcysteine in the treatment of glue ear: a double blind trial.

作者信息

Ramsden R T, Moffat D A, Gibson W P, Jay M M

出版信息

J Laryngol Otol. 1977 Oct;91(10):847-51. doi: 10.1017/s0022215100084462.

Abstract

A double blind trial was carried out comparing S-carboxymethylcysteine (S-CMC; Mucodyne, Berk Pharmaceuticals) with inert placebo in the treatment of glue ear in fifty-two children who had not previously undergone surgery for the condition. The results, analysed after three months of treatment failed to demonstrate a significant reduction in the number of children receiving S-CMC who eventually required surgery for the condition.

摘要

开展了一项双盲试验，将S-羧甲基半胱氨酸（S-CMC；沐舒坦，伯克制药公司）与惰性安慰剂进行比较，用于治疗52名此前未因该病接受过手术的儿童的胶耳。治疗三个月后进行分析的结果未能表明，接受S-CMC治疗的最终因该病需要手术的儿童数量有显著减少。