Array.
Antalya Training and Research Hospital; Department of Emergency Medicine.
Acta Biomed. 2020 Aug 25;92(1):e2021006. doi: 10.23750/abm.v92i1.9989.
In this study, we aimed to contribute to the literature by evaluating bonsai and additional drugs.
This prospective study was conducted on 217 patients who admitted to the emergency department (ED) with bonsai intake between December 20, 2014 and January 1, 2016, according to the patient history obtained from the patients. While 168 patients with negative urinary metabolites results were excluded from the study, 49 patients with positive urinary metabolites were included in the study. Patients were divided into two groups. The first group consisted of patients with only bonsai intake and the second group consisted of patients with bonsai and concomitant drug intake. The groups were compared in terms of symptoms, findings, blood gas values, duration of the symptoms, discharge time, hospitalization, and mortality rate. Data were analyzed using the Chi-square, the Fisher's exacttest, the Student t-test, and the Mann-Whitney U test. Data were evaluated at the 95% confidence interval. P<0.05 was considered statistically significant.
The mean age of 49 patients included in the study was 26.7±8.9 years and 91.8% (n=45) of the patients were male. Concomittant drug intake was identified in 69.4% of patients. Concomitant drug use was as follows: cocaine (20.4%, n=10), amphetamines (14.3%, n=7), methamphetamines (8,2%, n=4,) tetrahydrocannabinol (32.7%, n=16), opiates (18.4%, n=9) and alcohol (30.6%, n=15). On admission, Glasgow Coma Score (GCS) of the bonsai with additional substance group was significantly higher (p=0,003). The most common symptom was palpitations (tachycardia) (75.5%, n=37). There were no patients hospitalized in Only Bonsai group (p=0,020). The median time to remission of symptoms and median follow-up time of the patients in the emergency room were 3 hours and 6 hours, respectively. Remission time of the symptoms and hospitalization rates were higher in patients with concomittant drug intake (p <0.05) Conclusion: While the bonsai intake alone is not considered mortal to the patients and most of them can be discharged from the ED after signs and symptoms disappear, concomitant drug use can increase the toxic effects of bonsai intake. That is why follow-up of patients taking concomitant drug and the treatment process should be carried out more carefully.
在这项研究中，我们旨在通过评估盆景和其他药物来丰富文献。
这项前瞻性研究共纳入了 217 名于 2014 年 12 月 20 日至 2016 年 1 月 1 日因摄入盆景而到急诊科就诊的患者，根据患者病史进行评估。由于 168 名尿液代谢物结果为阴性的患者被排除在研究之外，因此最终纳入了 49 名尿液代谢物阳性的患者。将患者分为两组。第一组仅包括摄入盆景的患者，第二组包括摄入盆景和同时摄入其他药物的患者。比较两组患者的症状、检查结果、血气值、症状持续时间、出院时间、住院时间和死亡率。使用卡方检验、Fisher 确切检验、学生 t 检验和 Mann-Whitney U 检验进行数据分析。数据在 95%置信区间内进行评估。P<0.05 被认为具有统计学意义。
研究纳入的 49 名患者的平均年龄为 26.7±8.9 岁，91.8%（n=45）为男性。69.4%（n=34）的患者同时摄入其他药物。同时摄入的药物如下：可卡因（20.4%，n=10）、安非他命（14.3%，n=7）、甲基苯丙胺（8.2%，n=4）、四氢大麻酚（32.7%，n=16）、阿片类药物（18.4%，n=9）和酒精（30.6%，n=15）。入院时，同时摄入盆景和其他物质组的格拉斯哥昏迷评分（GCS）显著更高（p=0.003）。最常见的症状是心悸（心动过速）（75.5%，n=37）。仅摄入盆景组无患者住院（p=0.020）。急诊科患者症状缓解的中位时间和中位随访时间分别为 3 小时和 6 小时。同时摄入其他药物的患者症状缓解时间和住院率更高（p<0.05）。结论：虽然单独摄入盆景对患者不会致命，大多数患者在症状和体征消失后可以从急诊科出院，但同时摄入其他药物会增加盆景摄入的毒性作用。因此，应更仔细地对摄入其他药物的患者进行随访和治疗过程。
