Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Nanomedicine (Lond). 2021 Mar;16(6):497-516. doi: 10.2217/nnm-2020-0441. Epub 2021 Mar 8.
COVID-19, as an emerging infectious disease, has caused significant mortality and morbidity along with socioeconomic impact. No effective treatment or vaccine has been approved yet for this pandemic disease. Cutting-edge tools, especially nanotechnology, should be strongly considered to tackle this virus. This review aims to propose several strategies to design and fabricate effective diagnostic and therapeutic agents against COVID-19 by the aid of nanotechnology. Polymeric, inorganic self-assembling materials and peptide-based nanoparticles are promising tools for battling COVID-19 as well as its rapid diagnosis. This review summarizes all of the exciting advances nanomaterials are making toward COVID-19 prevention, diagnosis and therapy.
新型冠状病毒肺炎(COVID-19)作为一种新发传染病,造成了重大的病死率和发病率,对社会经济也产生了影响。目前尚未批准针对这种大流行疾病的有效治疗方法或疫苗。在应对这种病毒时,应强烈考虑使用尖端工具,特别是纳米技术。本综述旨在提出几种通过纳米技术设计和制备针对 COVID-19 的有效诊断和治疗剂的策略。聚合物、无机自组装材料和基于肽的纳米颗粒是抗击 COVID-19 及其快速诊断的有前途的工具。本综述总结了纳米材料在 COVID-19 预防、诊断和治疗方面取得的所有令人兴奋的进展。