Universidad Autonoma de Baja California (Facultad de Medicina Mexicali), Mexicali, Baja California, Mexico.
Centro de Investigacion en Artritis y Osteoporosis, Mexicali, Baja California, Mexico.
Arch Osteoporos. 2021 Mar 8;16(1):54. doi: 10.1007/s11657-021-00897-7.
"Dysmobility Syndrome" (DS) is a term that correlates sarcopenia and osteoporosis together with mobility disturbances, obesity, fractures, and falls. The prevalence of DS is of 74% in this study. Further research with bigger sample sizes is needed to describe if prevalence and DS characteristics are similar in other studies.
"Dysmobility Syndrome" (DS) correlates sarcopenia and osteoporosis together with mobility disturbances, obesity, fractures, and falls, all of which are related to adverse outcomes in the health of the elderly; however, there are no studies of DS in Mexican patients. In this study, we aimed to describe the characteristics of DS in Mexican postmenopausal women from a private practice.
A case-series study was conducted; women of 60 years and older were invited to participate from August to December of 2019, a total of 50 patients were included. Medical history, physical tests, bone densitometry, and body composition analysis were performed; patients who met 3 or more of the following criteria were diagnosed with DS: osteoporosis: T-score ≤ -2.5, falls in a previous year, lean appendicular mass: ≤ 5.45 kg/m, walking speed: < 1.0 m/s, grip strength: < 20 kg, and body fat percentage: > 40%.
Out of the total 50 patients, 37 were diagnosed with DS, with a prevalence of 74% in our study. Sixteen patients had a history of a non-vertebral fragility fracture, of which 14 had a diagnosis of DS (87%).
DS has a high frequency in our study group, and was found to be closely related to the presence of non-vertebral fragility fractures. More research is needed to describe the prevalence and characteristics of DS with a stronger statistical significance within our population, and among others across the country, to get an extensive understanding of its presentation in Mexican women.
• The frequency of DS in this study is higher than the one that is described in global literature. • DS diagnosis is closely related to the antecedent of non-vertebral fragility fracture.
“运动障碍综合征”（DS）将肌肉减少症和骨质疏松症与活动障碍、肥胖、骨折和跌倒联系在一起，所有这些都与老年人健康的不良后果有关；然而，在墨西哥患者中尚未有 DS 的研究。在这项研究中，我们旨在描述来自私人诊所的墨西哥绝经后妇女中 DS 的特征。
进行了病例系列研究；邀请 60 岁及以上的女性参加，于 2019 年 8 月至 12 月期间共有 50 名患者入组。进行了病史、体格检查、骨密度测定和身体成分分析；符合以下 3 项或以上标准的患者被诊断为 DS：骨质疏松症：T 评分≤-2.5，在过去一年中跌倒，四肢瘦组织质量：≤5.45kg/m，步行速度：<1.0m/s，握力：<20kg，体脂百分比：>40%。
在总共 50 名患者中，37 名被诊断为 DS，本研究中的患病率为 74%。16 名患者有非椎骨脆性骨折史，其中 14 名患有 DS（87%）。
在我们的研究组中，DS 的发病率很高，并且与非椎骨脆性骨折的存在密切相关。需要进一步研究以在我们的人群中以更强的统计学意义描述 DS 的患病率和特征，并在全国范围内的其他人群中进行描述，以更广泛地了解其在墨西哥女性中的表现。
• 本研究中 DS 的频率高于全球文献中描述的频率。• DS 诊断与非椎骨脆性骨折的病史密切相关。
