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种族与青少年特发性脊柱侧凸择期后路脊柱融合术早期结果的相关性:倾向匹配和亚组分析。

Association of Race with Early Outcomes of Elective Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: Propensity-Matched and Subgroup Analysis.

机构信息

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

World Neurosurg. 2021 Jun;150:e176-e181. doi: 10.1016/j.wneu.2021.02.113. Epub 2021 Mar 5.

Abstract

OBJECTIVE

To investigate the impact of race on 30-day postoperative complication rates of elective posterior spinal fusions (PSF) for adolescent idiopathic scoliosis (AIS).

METHODS

Patients who underwent PSF between 2012 and 2018 were reviewed from the American College of Surgeons National Surgical Quality Improvement Program pediatric database. Propensity score matching was utilized to evaluate whether patient race (i.e., black vs. white) was correlated with postoperative complications.

RESULTS

A total of 4051 PSF for AIS cases met criteria for inclusion. Of these, 3221 (79.5%) patients were white and 830 (20.5%) were black. Several baseline characteristics significantly differed between cohorts. Patients in the black cohort had a significantly higher body mass index, a greater proportion of female patients, higher ASA scores, preoperative diagnosis of asthma or cardiac risk factors, and prior use of steroids. The total number of vertebral segments fused was also greater in the black cohort. After controlling for differences in baseline characteristics with propensity score matching analysis, the only significant difference in morbidity and mortality identified was a higher incidence of venous thromboembolism among the black cohort (2.8% vs. 0.1%; P < 0.001).

CONCLUSIONS

In contrast to prior literature, our analysis did not identify black race as an independent risk factor for higher perioperative morbidity or mortality in patients of young age group undergoing elective PSF for AIS, except the higher incidence of venous thromboembolism. The findings of the present study suggest that previously reported perioperative morbidity and mortality outcomes in black patients may be secondary to baseline health characteristics, and not due to race itself.

摘要

目的

探讨种族对青少年特发性脊柱侧凸(AIS)后路脊柱融合术(PSF)术后 30 天并发症发生率的影响。

方法

从美国外科医师学会国家手术质量改进计划儿科数据库中回顾了 2012 年至 2018 年期间接受 PSF 的患者。利用倾向评分匹配评估患者种族(即黑人与白人)是否与术后并发症相关。

结果

共有 4051 例 AIS 的 PSF 病例符合纳入标准。其中 3221 例(79.5%)为白人,830 例(20.5%)为黑人。两组患者的基线特征存在显著差异。黑人组患者的体重指数更高,女性患者比例更高,ASA 评分更高,术前诊断为哮喘或存在心脏危险因素,以及术前使用过类固醇。黑人组融合的椎体节段总数也更多。通过倾向评分匹配分析控制基线特征差异后,发现仅黑人组的静脉血栓栓塞发生率更高(2.8%比 0.1%;P < 0.001)。

结论

与既往文献相比,我们的分析并未发现黑人种族是年轻 AIS 患者行 PSF 手术时围手术期发病率和死亡率较高的独立危险因素,除静脉血栓栓塞发生率较高外。本研究结果表明,先前报道的黑人患者围手术期发病率和死亡率较高的原因可能是基线健康特征所致,而不是种族本身。

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