State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing 100085, China.
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing 100085, China; School of Environment, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310000, China; College of Resource and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Environ Int. 2021 Jul;152:106450. doi: 10.1016/j.envint.2021.106450. Epub 2021 Mar 5.
Polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) are emerging persistent organic pollutants (POPs) that have similar or higher toxicities than the notorious dioxins. Toxicities, formation mechanisms, and environmental fates of PBDD/Fs are lacking because accurate quantification, especially of higher brominated congeners, is challenging. PBDD/F analysis is difficult because of photolysis and thermal degradation and interference from polybrominated diphenyl ethers. Here, literatures on PBDD/F analysis and environmental occurrences are reviewed to improve our understanding of PBDD/F environmental pollution and human exposure levels. Although PBDD/Fs behave similarly to dioxins, different congener profiles between PBDD/Fs and dioxins in the environment indicates their different sources and formation mechanisms. Herein, potential sources and formation mechanisms of PBDD/Fs were critically discussed, and current knowledge gaps and future directions for PBDD/F research are highlighted. An understanding of PBDD/F formation pathways will allow for development of synergistic control strategies for PBDD/Fs, dioxins, and other dioxin-like POPs.
多溴二苯并对二恶英和呋喃（PBDD/Fs）是新兴的持久性有机污染物（POPs），其毒性与臭名昭著的二恶英相似或更高。由于准确量化，特别是高溴化同系物的难度，因此 PBDD/F 的毒性、形成机制和环境归宿仍然缺乏了解。由于光解和热降解以及多溴联苯醚的干扰，PBDD/F 分析具有挑战性。本文综述了 PBDD/F 分析和环境出现的文献，以提高我们对 PBDD/F 环境污染和人类暴露水平的认识。尽管 PBDD/Fs 与二恶英的行为相似，但环境中二恶英和 PBDD/F 之间的不同同系物分布表明它们的来源和形成机制不同。本文批判性地讨论了 PBDD/Fs 的潜在来源和形成机制，并强调了当前 PBDD/F 研究的知识空白和未来方向。了解 PBDD/F 的形成途径将有助于制定针对 PBDD/Fs、二恶英和其他类似二恶英的 POPs 的协同控制策略。
