Wan H L, Lu G, Huang L, Ge L, Jiang Y Q, Di R Y, Zhang X L
Radiology Intervention Department, Huashan Hospital, Fudan University, Shanghai 200040, China.
Zhonghua Wai Ke Za Zhi. 2021 Mar 1;59(3):196-202. doi: 10.3760/cma.j.cn112139-20200818-00652.
To evaluate the safety and efficacy of stent-assisted coil embolization in patients with recurrent intracranial bifurcation aneurysms,after initial simple coiling or microsurgical clipping. Clinical data of 20 patients with recurrent intracranial bifurcation aneurysms who initially underwent simple coiling or surgical clipping and subsequently re-treated by stent-assisted coiling embolization at the Radiology Intervention Department of Huashan Hospital between March 2009 and November 2019 were collected and analyzed retrospectively.There were 9 males and 11 females,with a median age of 55.5 years (range:33 to 71 years),including 17 aneurysms initially treated with simple coiling and 3 treated with surgical clipping.All cases were re-treated with stent-assisted coiling,15 using a single stent and 5 employing two stents in a Y-configuration.Peri-and post-operative complications and outcomes were evaluated.Mann-Whitney tests were performed to compare the follow-up duration between initial treatment and re-treatment.Student's tests were used to compare the parent artery angles before re-treatment, after re-treatment and at the last follow-up. The parent artery angle was defined using the proximal main trunk and the stented branch. Immediate complete occlusion (Raymond Ⅰ) was achieved in 18 aneurysms (90.0%) while 2 aneurysms (10.0%) had a residual neck (Raymond Ⅱ).The median follow-up time(()) was 8.5(16.3)months,which had no significantly different from the initial treatment follow-up duration (15.5(27.0)months)(=157.7,=0.25). During the follow-up period,2 aneurysms (10.0%) with immediate post-operative residual necks recanalized again,including 1 aneurysm re-treated with the Y-configuration stent.Symptomatic thromboembolic complications occurred in 6 patients,including 4 re-treated with the Y-configuration stent.No peri-operative hemorrhagic complications occurred,along with no operation-related permanent disability or death. The parent artery angle increased significantly from pre-operative(90.1±21.1)°to post-operative and the last follow-up ((115.4±28.9)° and (132.6±26.8)°);=5.14,<0.01;=7.78,<0.01). For recurrent intracranial bifurcation aneurysms after initial surgical clipping or simple coiling,stent assisted coil embolization is proved to be safe and can decrease recurrence rate.
为评估支架辅助弹簧圈栓塞术在初次单纯弹簧圈栓塞或显微手术夹闭后复发的颅内分叉部动脉瘤患者中的安全性和有效性。收集并回顾性分析了2009年3月至2019年11月在华山医院放射介入科初次接受单纯弹簧圈栓塞或手术夹闭,随后接受支架辅助弹簧圈栓塞术再次治疗的20例复发颅内分叉部动脉瘤患者的临床资料。其中男性9例,女性11例,中位年龄55.5岁(范围:33至71岁),包括17例最初接受单纯弹簧圈栓塞治疗的动脉瘤和3例接受手术夹闭治疗的动脉瘤。所有病例均接受支架辅助弹簧圈栓塞术再次治疗,15例使用单个支架,5例采用Y形配置使用两个支架。评估围手术期和术后并发症及结果。采用Mann-Whitney检验比较初次治疗和再次治疗的随访时间。采用Student's检验比较再次治疗前、再次治疗后及末次随访时的载瘤动脉角度。载瘤动脉角度通过近端主干和置入支架的分支来定义。18例动脉瘤(90.0%)实现即刻完全闭塞(Raymond Ⅰ级),2例动脉瘤(10.0%)有残余瘤颈(Raymond Ⅱ级)。中位随访时间()为8.5(16.3)个月,与初次治疗随访时间(15.5(27.0)个月)无显著差异(=157.7,=0.25)。随访期间,2例术后即刻有残余瘤颈的动脉瘤(10.0%)再次发生再通,其中1例采用Y形配置支架再次治疗。6例患者出现有症状的血栓栓塞并发症,其中4例采用Y形配置支架再次治疗。未发生围手术期出血并发症,也没有与手术相关的永久性残疾或死亡。载瘤动脉角度从术前的(90.1±21.1)°显著增加至术后及末次随访时的((115.4±28.9)°和(132.6±26.8)°);=5.14,<0.01;=7.78,<0.01)。对于初次手术夹闭或单纯弹簧圈栓塞后复发的颅内分叉部动脉瘤,支架辅助弹簧圈栓塞术被证明是安全的,并且可以降低复发率。