Tan Chuen Wen, Fan Bingwen Eugene, Teo Winnie Z Y, Tung Moon Ley, Shafi Humaira, Christopher Dheepa, Zheng Shuwei, Peh Wee Ming, Chan Stephrene Seok Wei, Chong Vanessa Cui Lian, Gallardo Christian Aledia, Chang Cheng Chieh Ray, Ling Li Min, Tan Jing Yuan, Lee Ken Cheah Hooi, Phua Ghee Chee, Cherng Benjamin Pei Zhi, Low Jenny Guek Hong, Ho Vui Kian, Prasad Vishnu, Wong Lester Jung Long, Lim Cheryl Xiu Qi, Chee Yen Lin, Ong Kiat Hoe, Lee Lai Heng, Ng Heng Joo, Yap Eng Soo
Department of Haematology, Singapore General Hospital, Singapore, Singapore.
Department of Haematology, Tan Tock Seng Hospital, Singapore, Singapore.
Thromb J. 2021 Mar 8;19(1):14. doi: 10.1186/s12959-021-00268-9.
Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients.
This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. One hundred eleven patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n = 2) and 9.9% (n = 11), respectively. Major bleeding rate was 14.8% (n = 16).
Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.
据报道，动脉和静脉血栓形成在危重症COVID-19患者中很常见。
这是一项全国性多中心回顾性观察研究，纳入了2020年1月23日至2020年4月30日期间在新加坡所有因需要入住重症监护病房（ICU）而连续收治的成年COVID-19患者。共纳入111例患者，ICU中的静脉和动脉血栓形成率分别为1.8%（n = 2）和9.9%（n = 11）。大出血率为14.8%（n = 16）。
与其他报道的队列相比，新加坡的危重症COVID-19患者静脉血栓栓塞发生率较低，但动脉血栓形成率和出血表现较高。
