Department of Dentistry, Patna Medical College and Hospital, Patna, Bihar, India.
Department of Dentistry, Patna Medical College and Hospital, Patna, Bihar, India, Phone: +91 8971089231, e-mail:
J Contemp Dent Pract. 2020 Oct 1;21(10):1146-1149.
To compare the efficacy of 2% lignocaine and 4% articaine in the extraction of mandibular molars.
This study was conducted on 120 patients requiring surgical removal of tooth. Patients were categorized into 2 groups with 60 samples each. Group I patients were administered 2% lignocaine with 1:50,000 epinephrine and group II patients were administered 4% articaine with 1:100,000 epinephrine for the extraction of mandibular molar. Inferior alveolar nerve, lingual, and buccal nerve block used in both groups to anesthetize the area.
The mean onset of action in group I was 85.2 seconds and in group II was 52.6 seconds, duration of anesthesia in group I was 170.2 minutes and in group II was 226.8 minutes, duration of procedure was 30.4 minutes in group I and 32.6 minutes in group II, pain during procedure in group I was 2.75 and in group II was 1.42, pain after procedure was 1.41 in group I and 0.82 in group II, pain during anesthesia insertion was 1.52 in group I and 1.04 in group II. Forty-six (76.7%) patients in group I and 52 (86.7%) patients in group II did not require re-anesthesia, while 12 (20%) in group I and 8 (13.3%) in group II required 1 time re-anesthesia and 2 (3.3%) patients required 2 times re-anesthesia in group I.
Articaine can be effectively used in oral surgical procedures as there is early onset of action, longer duration of anesthesia, and less need of re-anesthesia.
Articaine is more effective compared to lignocaine, hence it can be recommended alternatively for tooth extraction and other oral surgical procedures.
比较 2%利多卡因和 4%阿替卡因在下颌磨牙拔除术中的疗效。
本研究纳入了 120 名需要手术拔牙的患者。将患者分为两组，每组 60 例。组 I 患者给予 2%利多卡因加 1:50000 肾上腺素，组 II 患者给予 4%阿替卡因加 1:100000 肾上腺素用于下颌磨牙拔除。两组均采用下牙槽神经、舌神经和颊神经阻滞麻醉。
组 I 的起效时间平均为 85.2 秒，组 II 为 52.6 秒，组 I 的麻醉持续时间为 170.2 分钟，组 II 为 226.8 分钟，组 I 的手术时间为 30.4 分钟，组 II 为 32.6 分钟，组 I 的手术过程中疼痛评分为 2.75，组 II 为 1.42，组 I 的术后疼痛评分为 1.41，组 II 为 0.82，组 I 的麻醉插入时疼痛评分为 1.52，组 II 为 1.04。组 I 中 46（76.7%）例患者和组 II 中 52（86.7%）例患者无需再次麻醉，组 I 中 12（20%）例患者和组 II 中 8（13.3%）例患者需要再次麻醉 1 次，组 I 中 2（3.3%）例患者需要再次麻醉 2 次。
阿替卡因可有效用于口腔外科手术，因为它起效迅速，麻醉持续时间长，且需要再次麻醉的次数较少。
阿替卡因比利多卡因更有效，因此可替代推荐用于拔牙和其他口腔外科手术。
