Infectious Diseases Department, Dijon Bourgogne University Hospital, 14 rue Paul Gaffarel, 21079, Dijon, France.
Department of Clinical Nephrology, Dijon Bourgogne University Hospital, Dijon, France.
Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2023-2028. doi: 10.1007/s10096-021-04216-3. Epub 2021 Mar 8.
During an epidemic period, we compared patients hospitalized for initial suspicion of COVID-19 but for whom an alternative diagnosis was finally retained (n = 152) with those who had COVID-19 (n = 222). Most common diagnoses were another infectious disease and heart failure. COVID-19-negative patients were more often active smokers had less often cough, fever, and digestive symptoms, as compared to the 222 COVID-19-positive patients. They had higher median neutrophil and lymphocyte counts and lower CRP level. In multivariate analysis, no current smoking, neurocognitive disorder, myalgia, and fibrinogen ≥4g/L were independently associated with a final diagnosis of COVID-19.
在流行期间,我们比较了因最初疑似 COVID-19 而住院但最终保留其他诊断的患者(n = 152)与 COVID-19 患者(n = 222)。最常见的诊断是另一种传染病和心力衰竭。与 222 例 COVID-19 阳性患者相比,COVID-19 阴性患者中经常吸烟者更少出现咳嗽、发热和消化症状。他们的中性粒细胞和淋巴细胞计数中位数更高,CRP 水平更低。多变量分析显示,无当前吸烟、神经认知障碍、肌痛和纤维蛋白原≥4g/L 与最终 COVID-19 诊断独立相关。