Plaçais L, Richier Q
Médecine interne, Sorbonne Université, 15-21, rue de l'École-de-médecine, 75006 Paris, France.
Médecine interne, Université de Paris, 12, rue de l'École-de-médecine, 75006 Paris, France.
Rev Med Interne. 2020 May;41(5):308-318. doi: 10.1016/j.revmed.2020.04.004. Epub 2020 Apr 17.
The spread of the new coronavirus SARS-CoV-2, discovered in China in January 2020, led to a pandemic as early as March 2020, forcing every health care system in the affected countries to adapt quickly. In order to better address this major health crisis, which has given rise to numerous scientific publications, we have synthesized the main original clinical studies to facilitate the day-to-day management of patients with COVID-19. We detail the early signs and progression of the disease as well as the different clinical forms, including extra-pulmonary, as known at the beginning of this pandemic. We focus on clinical, biological and CT markers predictive of severity or mortality. Finally, we discuss the impact of SARS-CoV-2 infection in populations suspected to be at high risk of severe forms.
2020年1月在中国发现的新型冠状病毒SARS-CoV-2的传播，早在2020年3月就引发了一场大流行，迫使受影响国家的每个医疗系统迅速做出调整。为了更好地应对这一引发了众多科学出版物的重大健康危机，我们综合了主要的原始临床研究，以促进COVID-19患者的日常管理。我们详细介绍了该疾病的早期症状和进展以及不同的临床形式，包括在这场大流行开始时已知的肺外表现。我们重点关注预测严重程度或死亡率的临床、生物学和CT标志物。最后，我们讨论了SARS-CoV-2感染对疑似有严重形式高风险人群的影响。
