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肺腺样囊性癌双侧肾脏转移:一例病例报告并文献复习。

Bilateral kidney metastases from adenoid cystic carcinoma of lung: a case report and literature review.

机构信息

Department of Urology, Onze-Lieve-Vrouw Hospital, Moorselbaan 164, 9300, Aalst, Belgium.

Division of Urology, IRCCS Azienda Ospedaliero, Universitaria di Bologna, Bologna, Italy.

出版信息

CEN Case Rep. 2021 Nov;10(4):468-472. doi: 10.1007/s13730-021-00589-8. Epub 2021 Mar 8.

Abstract

Adenoid cystic carcinoma (ACC) is a rare malignant tumor, usually arising from salivary glands and rarely found in other locations. ACC is characterized by asymptomatic course, slow growth pattern, perineural invasion and high incidence of late metastasis. Renal localization of metastasis is rare. Only 12 cases of renal metastasis were published and, to our best knowledge, no case of bilateral metastasis to the kidney has ever been reported. We present a case of a 58 years old woman with bilateral renal metastasis from ACC of the right lung after fourteen years from lobectomy and radiotherapy for the primary presentation. The patient underwent bilateral robot-assisted partial nephrectomy in a two-stage approach. Despite its rare incidence and slow growth, ACC metastasis may simulate primary papillary renal carcinoma and occur many years after primary treatment. Therefore, lifelong follow-up, including abdominal imaging, is recommended.

摘要

腺样囊性癌(ACC)是一种罕见的恶性肿瘤,通常发生于唾液腺,很少发生于其他部位。ACC 的特点为无症状病程、缓慢生长模式、神经周围侵犯和晚期转移发生率高。肾脏转移部位罕见。仅有 12 例肾脏转移的病例发表,据我们所知,从未有过双侧肾脏转移的病例报告。我们报告了一例 58 岁女性患者,14 年前因右肺 ACC 行肺叶切除术和放疗,14 年后出现双侧肾脏转移。患者行双侧机器人辅助部分肾切除术,分两阶段进行。尽管 ACC 转移的发生率低且生长缓慢,但它可能模拟原发性乳头状肾癌,并在初次治疗后多年发生。因此,建议终身随访,包括腹部影像学检查。

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