Fernandez Manso Beatriz, Barrio Torres Josefa, Martinez Escribano Beatriz, Perez Fernandez Cristina
Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain
Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.
BMJ Case Rep. 2021 Mar 9;14(3):e239980. doi: 10.1136/bcr-2020-239980.
An 11-year-old boy with a history of atopy and allergic rhinitis under treatment with sublingual immunotherapy was referred following several episodes of food impaction. Diagnosis of eosinophilic oesophagitis, chronic gastritis and gastric mucosa-associated lymphoid tissue (MALT) lymphoma associated to were confirmed. Results of the extension study were negative and the lymphoma was resolved with eradicating treatment for No improvement was observed in the oesophagitis after the withdrawal of immunotherapy and treatment with high proton pump inhibitor doses or following the omission of several foods to which subclinical sensitisation was confirmed. Oesophagitis was finally resolved by removing cow's milk protein. After 10 years, neither eosinophilic oesophagitis nor MALT lymphoma was observed.Gastric MALT lymphoma associated to is a rare disorder in children. Although coexisting infection is common in patients with eosinophilic oesophagitis, the association of gastric MALT lymphoma with eosinophilic oesophagitis has not been reported before.
一名11岁有特应性病史且正在接受舌下免疫治疗的变应性鼻炎男孩，在经历几次食物嵌塞后前来就诊。嗜酸性粒细胞性食管炎、慢性胃炎以及与……相关的胃黏膜相关淋巴组织（MALT）淋巴瘤的诊断得到证实。扩展研究结果为阴性，淋巴瘤通过针对……的根除治疗得以缓解。在停用免疫治疗、高剂量质子泵抑制剂治疗或排除几种已证实存在亚临床致敏的食物后，食管炎未见改善。最终通过去除牛奶蛋白，食管炎得以缓解。10年后，未观察到嗜酸性粒细胞性食管炎或MALT淋巴瘤。与……相关的胃MALT淋巴瘤在儿童中是一种罕见疾病。虽然嗜酸性粒细胞性食管炎患者中合并……感染很常见，但胃MALT淋巴瘤与嗜酸性粒细胞性食管炎的关联此前尚未见报道。
