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巨大肾上腺囊肿与显著低肾素性醛固酮增多症并存

Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism.

作者信息

Sakaue Takaaki, Okuno Yosuke, Mukai Kosuke, Fujita Shingo, Kozawa Junji, Nishizawa Hitoshi, Matsuoka Taka-Aki, Iwahashi Hiromi, Norikazu Maeda, Yamazaki Yuto, Sasano Hironobu, Otsuki Michio, Shimomura Iichiro

机构信息

Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

出版信息

Case Rep Endocrinol. 2021 Feb 20;2021:8860498. doi: 10.1155/2021/8860498. eCollection 2021.

DOI:10.1155/2021/8860498
PMID:33688442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7914103/
Abstract

A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

摘要

一名患有终末期肾病的67岁日本女性因肾移植被转诊至我院。腹部CT显示一个大的肾上腺肿块，密度不均匀。她有中风和心力衰竭住院史，表现为明显的低肾素性醛固酮增多症。用抗CYP11B2抗体对切除的肿瘤进行组织学检查表明，她患有因多个肾上腺皮质微结节导致的伴有原发性醛固酮增多症（PA）的血管内皮囊肿。本报告提示肾上腺血管囊肿与PA介导的肾上腺静脉血管损伤之间存在病理相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/7a9ec4a18784/CRIE2021-8860498.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/9d9f00ba9a9f/CRIE2021-8860498.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/e48f3231312c/CRIE2021-8860498.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/7a9ec4a18784/CRIE2021-8860498.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/9d9f00ba9a9f/CRIE2021-8860498.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/e48f3231312c/CRIE2021-8860498.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/7914103/7a9ec4a18784/CRIE2021-8860498.003.jpg

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