BJS Open. 2021 Mar 5;5(2). doi: 10.1093/bjsopen/zraa025.
The Vascular Research Collaborative was established to develop a national research strategy for patients with vascular disease in the UK. This project aimed to establish national research priorities in this patient group.
A modified Delphi approach, an established method for reaching a consensus opinion among a group of experts in a particular field, was used to survey national multidisciplinary vascular clinical specialists. Two rounds of online surveys were conducted involving the membership of the Vascular Society, Society of Vascular Nurses, Society for Vascular Technology, and the Rouleaux Club (vascular surgical trainees). The first round invited any suggestions for vascular research topics. A steering group then collated and rationalized the suggestions, categorizing them by consensus into pathological topics and research categories, and amalgamating the various questions relating to the same fundamental issue into a single question. The second round involved recirculating these questions to the same participants for priority scoring.
Round 1 resulted in 1231 suggested research questions from 481 respondents. Steering group collation and rationalization resulted in 83 questions for ranking in round 2. The second round resulted in a hierarchical list of vascular research priorities. The highest scoring priorities addressed topics related to critical lower-limb ischaemia, diabetic foot disease, amputation, wound healing, carotid plaque morphology, and service organization/delivery.
It is anticipated that these results will drive the UK national vascular research agenda for the next 5-10 years. It will facilitate focused development and funding of new research projects in current clinical areas of unmet need where potential impact is greatest.
血管研究协作组织成立的目的是为英国血管疾病患者制定国家研究战略。本项目旨在确定该患者群体的国家研究重点。
采用改良 Delphi 法,这是一种在特定领域的专家组中达成共识意见的成熟方法,对英国多学科血管临床专家进行了调查。进行了两轮在线调查,涉及血管学会、血管护士学会、血管技术学会和 Rouleaux 俱乐部(血管外科培训生)的成员。第一轮邀请对血管研究课题提出任何建议。指导小组随后对建议进行整理和合理化,根据共识将其分为病理主题和研究类别,并将与同一基本问题相关的各种问题合并为一个问题。第二轮将这些问题重新分发给同一批参与者进行优先排序。
第一轮从 481 名受访者中提出了 1231 个研究问题。指导小组的整理和合理化产生了第二轮排名的 83 个问题。第二轮产生了血管研究重点的层次结构列表。得分最高的重点涉及与严重下肢缺血、糖尿病足病、截肢、伤口愈合、颈动脉斑块形态和服务组织/交付相关的主题。
预计这些结果将推动英国未来 5-10 年的国家血管研究议程。它将促进在潜在影响最大的现有临床未满足需求领域集中开发和资助新的研究项目。