Haritoglou C, Hubschman J P, Schumann R G, Maier M
Augenklinik Herzog Carl Theodor, Nymphenburger Str. 43, 80335, München, Deutschland.
Retina Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, USA.
Ophthalmologe. 2021 Apr;118(4):308-319. doi: 10.1007/s00347-021-01349-w. Epub 2021 Mar 10.
Using high-resolution imaging, such as optical coherence tomography (OCT), the different layers of the retina as well as the vitreoretinal interface and its alterations can be very clearly differentiated. This includes the morphological characteristics of tractive maculopathies, such as epiretinal gliosis and vitreomacular traction syndrome. Additionally, structural alterations of the various layers of the neurosensory retina as a result of traction due to these pathologies can be demarcated. The latter have been investigated in clinical trials and evaluated as OCT biomarkers with respect to their prognostic and predictive value. In this review we would like to present and discuss various OCT biomarkers in the context of epimacular membranes and vitreomacular traction syndrome.
使用高分辨率成像技术，如光学相干断层扫描（OCT），可以非常清晰地区分视网膜的不同层以及玻璃体视网膜界面及其改变。这包括牵引性黄斑病变的形态学特征，如视网膜前胶质增生和玻璃体黄斑牵引综合征。此外，由于这些病变引起的牵引导致的神经感觉视网膜各层的结构改变也可以被界定。后者已在临床试验中进行了研究，并作为OCT生物标志物对其预后和预测价值进行了评估。在本综述中，我们将在黄斑前膜和玻璃体黄斑牵引综合征的背景下介绍和讨论各种OCT生物标志物。
