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微创修复重大先天性畸形后的利用、住院时间和并发症的基准测试。

Benchmarking utilization, length of stay, and complications following minimally invasive repair of major congenital anomalies.

机构信息

Center for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, 611 Livingston Avenue, Suite 3A.3, Columbus, OH, 43205, USA.

Center for Innovation in Pediatric Practice, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

出版信息

Surg Endosc. 2022 Feb;36(2):1633-1649. doi: 10.1007/s00464-021-08413-1. Epub 2021 Mar 10.

Abstract

INTRODUCTION

Infants with newborn congenital anomalies are increasingly undergoing minimally invasive surgical (MIS) repair. Currently available data on outcomes are limited. This study provides national estimates for length of stay and 30-day complications following MIS for congenital anomalies.

METHODS

Using the ACS-NSQIP Pediatric (2013-2018), a retrospective analysis of MIS for congenital anomalies was performed. MIS repairs for the following diagnoses were included: pyloric stenosis (PS), congenital lung lesion (LL), mediastinal mass (MM), congenital malrotation (CM), anorectal malformation (ARM), Hirschsprung's disease (HD), congenital diaphragmatic hernia (CDH), tracheoesophageal fistula (TEF), biliary atresia/choledochal cyst (HB), and intestinal atresia (IA). Postoperative LOS (pLOS) and complication rates were examined using multivariable analysis for risk factors after categorizing surgeries by complexity of care related to congenital anomaly: Simple (PS), Complex Group 1 (LL, MM, CM, and ARM), and Complex Group 2 (HD, CDH, TEF, HB, and IA).

RESULTS

Across 10 anomalies, 8,326 repairs were performed using an MIS approach. Procedure-specific median postoperative LOS (75th-percentile, 90th-percentile) for PS was 1 day (1, 3); LL was 3 (4, 7); MM was 2 (3, 5); CM was 4 (7, 14); ARM was 3 (5, 8); HD was 5 (8, 12); CDH was 8 (18, 31); HB was 5 (8, 12); TEF was 20 (31, 53); and IA was 17 (25, 40). The overall surgical complication rates (95% CI) were: PS, 5.1% (4.7%-5.6%); LL, 14.2% (12.3-16.4); MM, 8.4% (6.4-11.0); CM, 14.6% (11.9-17.9); ARM, 12.0% (7.1-19.5); HD, 22.1% (19.5-25.0); CDH, 21.1% (17.1-25.6); HB, 20.6% (13.7-29.7); TEF, 36% (27.5-45.5); and IA, 28.6% (19.3-40.1). Risk factors for increased pLOS and complications varied by procedure category and included patient-level and admission characteristics.

CONCLUSION

This study provides national benchmarks and risk factors for expected postoperative LOS and 30-day complications following MIS for congenital anomalies.

摘要

简介

越来越多的新生儿先天性畸形患儿接受微创外科(MIS)修复。目前可用的结局数据有限。本研究提供了先天性畸形 MIS 术后住院时间和 30 天并发症的全国估计值。

方法

使用 ACS-NSQIP 儿科(2013-2018 年),对先天性畸形的 MIS 进行了回顾性分析。纳入了以下诊断的 MIS 修复:幽门狭窄(PS)、先天性肺病变(LL)、纵隔肿块(MM)、先天性旋转不良(CM)、肛门直肠畸形(ARM)、先天性巨结肠(HD)、先天性膈疝(CDH)、气管食管瘘(TEF)、胆道闭锁/胆管囊肿(HB)和肠闭锁(IA)。使用多变量分析,根据与先天性异常相关的护理复杂性对手术进行分类后,检查了术后住院时间(pLOS)和并发症发生率:简单(PS)、复杂组 1(LL、MM、CM 和 ARM)和复杂组 2(HD、CDH、TEF、HB 和 IA)。

结果

在 10 种异常中,8326 例采用 MIS 方法进行了修复。PS 的特定手术术后中位住院时间(第 75 百分位数,第 90 百分位数)为 1 天(1、3);LL 为 3 天(4、7);MM 为 2 天(3、5);CM 为 4 天(7、14);ARM 为 3 天(5、8);HD 为 5 天(8、12);CDH 为 8 天(18、31);HB 为 5 天(8、12);TEF 为 20 天(31、53);IA 为 17 天(25、40)。总体手术并发症发生率(95%CI)为:PS,5.1%(4.7%-5.6%);LL,14.2%(12.3-16.4);MM,8.4%(6.4-11.0);CM,14.6%(11.9-17.9);ARM,12.0%(7.1-19.5);HD,22.1%(19.5-25.0);CDH,21.1%(17.1-25.6);HB,20.6%(13.7-29.7);TEF,36%(27.5-45.5);IA,28.6%(19.3-40.1)。手术类别不同,pLOS 和并发症增加的风险因素也不同,包括患者水平和入院特征。

结论

本研究提供了先天性畸形 MIS 术后住院时间和 30 天并发症的全国性基准和风险因素。

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