Lefeuvre Lucie, Dan Diana
Service de rhumatologie, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.
Rev Med Suisse. 2021 Mar 10;17(729):492-496.
The connectivitides are autoimmune diseases that affect many organs. All of them can cause interstitial lung disease, the most frequent forms being the NSIP (nonspecific interstitial pneumonia) and the UIP (usual interstitial pneumonia). The best screening method is the high-resolution chest CT. The treatment of ILD includes glucocorticoids, immunosuppressive and antifibrotic agents, as well as non-pharmacological therapies. We present the screening and treatment algorithm for the ILD in systemic sclerosis, which is very well established. We also discuss the management of the ILD in rheumatoid arthritis, a very prevalent disease, and though of large public interest.
结缔组织病是影响多个器官的自身免疫性疾病。它们都可导致间质性肺疾病，最常见的类型是非特异性间质性肺炎（NSIP）和寻常型间质性肺炎（UIP）。最佳筛查方法是高分辨率胸部CT。间质性肺疾病的治疗包括糖皮质激素、免疫抑制剂和抗纤维化药物，以及非药物治疗。我们展示了系统性硬化症中间质性肺疾病的筛查和治疗算法，该算法已非常成熟。我们还讨论了类风湿关节炎中间质性肺疾病的管理，类风湿关节炎是一种非常常见且备受公众关注的疾病。
