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新型冠状病毒肺炎病程中的主动脉血栓形成;两例罕见病例。

Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases.

作者信息

Çora Ahmet Rıfkı, Çelik Ersin, Karadem Kadir Burhan

机构信息

Isparta City Hospital Cardiovascular Surgery Clinic, Isparta, Turkey.

Isparta City Hospital Cardiovascular Surgery Clinic, Isparta, Turkey.

出版信息

Ann Vasc Surg. 2021 May;73:119-121. doi: 10.1016/j.avsg.2021.02.007. Epub 2021 Mar 6.

Abstract

OBJECTIVE

Acute aortic thrombosis and floating aortailiac thrombus are infrequent clinical conditions with high morbidity and mortality rates. It was observed that; SARS-CoV-2 coronavirus disease (Covid-19) caused a hyperinflammation and hyperimmune state and these conditions can result in a hypercoagulation and eventually thrombotic events might occur.

METHODS

Here we presented two covid-19 positive patients with rare aortic thrombotic events.

RESULTS

Two patients underwent emergent diagnostic tests including computerized tomographic angiography. Total aortic thrombosis just below the renal arising point was evaluated in one patient, and aortic floating thrombus was evaluated in other patient. But despite initial medical therapies, the clinical conditions of the cases worsened and both patients died while on medical therapy before planned surgical intervention applied.

CONCLUSIONS

Covid-19 is not only the disease of lungs and inflammatory system also the disease of coagulation and vascular system. Aortic thrombosis is rare and must be kept in mind in Covid-19 patients with peripheral circulation impairment.

摘要

目的

急性主动脉血栓形成和漂浮性主-髂动脉血栓是临床罕见的疾病,发病率和死亡率很高。据观察,严重急性呼吸综合征冠状病毒2型冠状病毒病(Covid-19)会引发炎症反应过度和免疫状态亢进,这些情况可导致血液高凝,最终可能发生血栓形成事件。

方法

在此,我们报告了2例Covid-19阳性且发生罕见主动脉血栓形成事件的患者。

结果

2例患者均接受了包括计算机断层血管造影在内的紧急诊断检查。1例患者评估为肾动脉起始点下方的全主动脉血栓形成,另1例患者评估为主动脉漂浮血栓。但尽管进行了初始药物治疗,病例的临床状况仍恶化,2例患者在计划的手术干预实施前接受药物治疗时均死亡。

结论

Covid-19不仅是肺部和炎症系统疾病,也是凝血和血管系统疾病。主动脉血栓形成罕见,在有外周循环障碍的Covid-19患者中必须予以关注。

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