Wang Hao, Tarriela Joseph, Shiveshwarkar Priyanka, Pyayt Anna
Appl Opt. 2021 Jan 20;60(3):593-599. doi: 10.1364/AO.408577.
It has been demonstrated that optically controlled microcurrents can be used to capture and move around a variety of microscopic objects ranging from cells and nanowires to whole live worms. Here, we present our findings on several new regimes of optofluidic manipulation that can be engineered using careful design of microcurrents. We theoretically optimize these regimes using COMSOL Multiphysics and present three sets of simulations and corresponding optofluidic experiments. In the first regime, we use local fluid heating to create a microcurrent with a symmetric toroid shape capturing particles in the center. In the second regime, the microcurrent shifts and tilts because external fluid flow is introduced into the microfluidic channel. In the third regime, the whole microfluidic channel is tilted, and the resulting microcurrent projects particles in a fan-like fashion. All three configurations provide interesting opportunities to manipulate small particles in fluid droplets and microfluidic channels.
已经证明,光控微电流可用于捕获和移动各种微观物体,从细胞、纳米线到整条活蠕虫。在此,我们展示了关于光流体操纵几种新机制的研究结果,这些机制可通过精心设计微电流来构建。我们使用COMSOL Multiphysics对这些机制进行了理论优化,并展示了三组模拟和相应的光流体实验。在第一种机制中,我们利用局部流体加热来创建一个具有对称环形形状的微电流,将粒子捕获在中心。在第二种机制中,由于外部流体流入微流体通道,微电流发生偏移和倾斜。在第三种机制中,整个微流体通道倾斜,产生的微电流以扇形方式投射粒子。所有这三种配置都为在液滴和微流体通道中操纵小粒子提供了有趣的机会。